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. 2023 Jun 13;6:638. doi: 10.1038/s42003-023-05011-w

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a, d UMAPs of FAP clusters in human and mouse separated by obesity status. b, c The effects of obesity on the proportions of FAP clusters 1, 4, and 6 in humans and mice. e, f The effects of sex on the proportions of FAP clusters 1, 4, and 6 in humans and mice. Values are mean ± SD. n = 4 lean and 5 obese for (b); n = 4 females and 5 males for (e) and n = 1 pooled sample from n = 10 male mice and n = 1 pooled sample from n = 10 female mice fed either a normal chow diet (NCD) or a high-fat diet (HFD) for (c, f).