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. 2023 Jun 13;14:3502. doi: 10.1038/s41467-023-38922-7

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a Distribution of annotated genes, high-copy centromeric Chio satellite repeats, and transposable elements (TEs), as well as the enrichment of CENH3, H3K9me2, and H3K4me2 ChIPseq. The ChIPseq signal tracks are represented as the average log₂ ratio of ChIP/input in genome-wide 10 kb windows. Chromosome 2 is taken as a representative chromosome. DNA methylation level at CpG, CHG, and CHH is shown in percentage. b Genome-wide enrichment of CENH3, H3K4me2, and H3K9me2 at different types of sequences, including genes (blue), centromeric Chio satellite arrays (green), and TEs (black). c The heatmap shows the correlation scores among different ChIPseq samples (CENH3, H3K9me2 and H3K4me2) and transcriptome. d The methylation level of CpG, CHG, and CHH at genes (blue), Chio arrays (green), and TEs (black).