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. 2023 Jun 13;14:3502. doi: 10.1038/s41467-023-38922-7

Fig. 8. A simplified model of the dynamic organization of centromere units and intercentromeric regions at pachytene, mitotic metaphase and interphase of C. japonica.

Fig. 8

a Each C. japonica chromatid harbors 7–11 evenly spaced megabase-sized centromeric units (red) separated by intercentromeric regions (gray). At pachytene, the chromosome is decondensed and individual centromere units are distinguishable. b At interphase, centromeric units cluster into a few chromocenters per chromatid. c At metaphase, centromeric units form a line-like holocentromere at the periphery of chromosomes. ac Overlapping of CENH3-containing nucleosomes indicates a higher condensation degree of centromeric chromatin.