Figure 3.

NLRC5 Deficiency Promoted the Infiltration of Immune Cells After TAC Operation

(A and B) Representative cytograms and quantitative analysis of F4/80⁺ CD64⁺MerTK⁺ macrophages in heart tissues (n = 10 per group). (C and D) Representative cytograms and quantitative analysis of CCR2⁺Timd4⁻ macrophages in heart tissues (n = 10 per group). (E and F) Representative cytograms and quantitative analysis of Ly6G⁺ neutrophils in heart tissues (n = 10 per group). (G and H) Quantitative analysis of Ly6G⁺ neutrophils (G) and Ly6C⁺ monocytes (H) in peripheral blood after 1 week of TAC (n = 10 per group). (I to K) Quantitative analysis of CD3⁺ T cells (I), CD4⁺ T cells (J), and CD8⁺ T cells (K) in heart tissues after 4 weeks of TAC. (L to N) Quantitative analysis of CD3⁺ T cells (L), CD4⁺ T cells (M), and CD8⁺ T cells (N) in peripheral blood after 4 weeks of TAC (n = 10 per group). Data are expressed as mean ± SD. ∗P < 0.05, ∗∗P < 0.01. Data were analyzed using 1-way analysis of variance followed by Tukey’s post hoc analysis. Abbreviations as in Figure 2.