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. 2023 May 31;10:1205434. doi: 10.3389/fnut.2023.1205434

Table 1.

Characteristics of studies and participants.

No Study Type of study Country Follow-up duration Intervention Group Subject (n) Participant characteristics
Age (years) Gender BMI (kg/m 2 ) Weight (kg)
1 Othman et al. (65) Clinical trial Tunisia 1 month Probiotic: 1 tablet containing Bifidobacterium longum, Lactobacillus helveticus, Lactococcus lactis, Streptococcus thermophilus/day 15 48.73 ± 7.7 (mean ± SD) Female 93.3% (n = 42) Male 6.7% (n = 3) ≥30 (no information for mean and SD) 106.09 (no information for SD)
Diet only (low-carbohydrate and reduced energy diet) 15 103.7 (no information for SD)
2 Sanchez et al. (66) RCT Canada Phase 1 = 12 weeks
Phase 2 = 12 weeks
Probiotic: 2 capsules containing LPR (Lactobacillus rhamnosus)/day 62 35 ± 10.0 (mean ± SE) Male:24 Female:38 33.8 ± 3.3 (mean ± SE) 95.1 ± 13.9 (mean ± SE)
Placebo 63 37 ± 10.0 (mean ± SE) Male:24 Female:39 33.3 ± 3.2 (mean ± SE) 94.0± 14.9 (mean ± SE)
3 Akkasheh et al. (67) RCT Iran 8 weeks Probiotic: 1 capsule containing Lactobacillus acidophilus, Lactobacillus casei, Bifidobacterium bifidum/day 20 38.3 ± 12.1 (mean ± SD) Female 85% (n = 17) Male 15% (n = 3) 27.6 ± 6.0 (mean ± SD) 72.6 ± 11.3 (mean ± SD)
Placebo (starch) 20 36.2 ± 8.2 (mean ± SD) Female 85% (n = 17) Male 15% (n = 3) 26.3 ± 4.1 (mean ± SD) 68.0 ± 11.5 (mean ± SD)

BMI, Body Mass Index; RCT, Randomized Controlled Trial.