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Summary of VH-04’s effects on biochemical and morphological parameters.
| Parameter | Method | Species | Result |
|---|---|---|---|
| Age-related changes in hippocampal metabolic profile | 1H-magnetic resonance spectroscopy | Rats | No effect |
| Aged-related synaptic changes inferred from hippocampal synaptophysin mRNA expression | RT-qPCR | Rats | Possible improvement: p = 0.0847 (vehicle- vs. VH-04-treated aged rats) |
| Primary hippocampal neurite elongation | NeuronJ plugin to measure neurite length | Mice | Improvement |
