eTable 1. Definition of the Revised International Prognostic Scoring System (IPSS-R) (26).
| 0 | 0.5 | 1 | 1.5 | 2 | 3 | 4 | |
| Karyotype | *1 | *2 | *3 | *4 | *5 | ||
| Blasts (%) | ≤ 2 | > 2 ≤ 5 | 5–10 | > 10 | |||
| Hb concentration (g/dL) | ≥ 10 | 8 10 | < 8 | ||||
| Platelets (/nL) | ≥ 100 | 50 ≤ 100 | < 50 | ||||
| Neutrophils (/nL) | ≥ 0.8 | < 0.8 | |||||
| Risk score | Points | Median survival (years) | |||||
| “very low risk” | ≤ 1.5 | 9.00 | |||||
| “low risk” | 2–3 | 5.63 | |||||
| “intermediate risk” | 3.5–4.5 | 2.63 | |||||
| “high risk” | 5–6 | 1.28 | |||||
| “very low risk” | > 6 | 0.85 | |||||
*1 Very good (-Y, del[11q])
*2 Good (normal, del[5q], del[12p], del[20q], double clone with del[5q] except chromosome 7)
*3 Intermediate (del[7q], +8, +19, i[17q], other single or double clones)
*4 Poor (-7, inv(3)/t(3q)/del(3q), double clone with –7/del(7q), complex with max. 3 aberrations)
*5 Very poor (complex with more than 3 aberrations)