Table 1.

Clinical characteristics of Japanese PBC cases.

	PBC (n=1670)
Age (years), median(range)	57 (22-89)
Female (%)	85.9
AST (IU/L), (mean ± SD)	55 ± 88
ALP (IU/L), (mean ± SD)	580 ± 411
IgM (mg/dL), (mean ± SD)	353 ± 257
IgG (mg/dL), (mean ± SD)	1640 ± 519
Anti-gp210 antibodies positive (%)	25.9
Anti-mitochondrial antibodies positive (%)	88.3
Anti-nuclear antibodies positive (%)	72.5
Scheuer stage 1-2/3-4 (%)	81.8/18.2
Severity
aPBC/s0,1, 2 (%)	66.4/33.6
Concomitant disease
autoimmune hepatitis (%)	7.2
other autoimmune diseases (%)	20.9
Clinical outcome
hepatocellular carcinoma (%)	3.1
liver transplantation and/or death by hepatic failure (%)	8.4