Table 3A.
Multivariate linear regression for iPTH.
| Independent variable | 25(OH)D | 95%CI | Independent variable | 1,25(OH)2D | |||
|---|---|---|---|---|---|---|---|
| p value | Coefficients B | p value | Coefficients B | 95%CI | |||
| Constant | 21×10-6 | 88.333 | 47.957~128.709 | 0.005 | 87.398 | 25.874~148.922 | |
| Age | 0.166 | 0.141 | -0.059~0.341 | 0.806 | 0.040 | -0.279~0.359 | |
| iPTH | 53×10-6 | -0.094 | -0.139~-0.049 | 0.243 | 0.043 | -0.029~0.114 | |
| Serum Calcium | 0.212 | -9.443 | -24.275~5.389 | 0.195 | 14.980 | -7.732~37.692 | |
| Serum Phosphor | 0.118 | -9.597 | -21.640~2.445 | 0.153 | -13.775 | -32.712~5.161 | |
| Serum Creatinine | 0.169 | 3.352 | -1.431~8.134 | 0.000 | -16.582 | -24.505~-8.660 | |
| FGF23 | 0.205 | 0.109 | -0.060~0.279 | 0.024 | -0.296 | -0.553~-0.039 | |
| OPG | 0.038 | -1.295 | -2.516~-0.074 | 0.799 | -0.255 | -2.219~1.709 | |
| ALP | 0.647 | -0.017 | -0.091~0.056 | 0.035 | 0.130 | 0.009~0.251 | |
| Sclerostin | 0.717 | -0.019 | -0.124~0.086 | 0.107 | -0.130 | -0.289~0.028 |
25(OH)D, 25-hydroxy-vitamin D; 1,25(OH)2D, 1,25-dihydroxyvitamin D; iPTH, intact parathyroid hormone; FGF23, Fibroblast Growth Factor 23 receptor; OPG, osteoprotegerin; ALP, alkaline phosphatase.
Coefficients B: unstandardized coefficients B.
95%CI: 95% Confidence interval for B.
Parameters recognized in the literature as affecting PTH concentration (age, serum calcium, serum phosphor, creatinine, FGF23, OPG, ALP, and sclerostin) were introduced into the multivariate linear regression model.