Table 4A.
Multivariate linear regression for iPTH in vitamin D sufficient/deficient group.
| Independent variable | 25(OH)D≥30ng/mL | Independent variable | 25(OH)D<30ng/mL | ||||
|---|---|---|---|---|---|---|---|
| p value | Coefficients B | 95%CI | p value | Coefficients B | 95%CI | ||
| Constant | 10×10-6 | 92.179 | 51.850~132.507 | 0.646 | -4.639 | -24.680~15.402 | |
| Age | 0.552 | -0.066 | -0.282~0.151 | 0.092 | 0.076 | -0.013~0.164 | |
| 1,25(OH)2D | 0.005 | 0.093 | 0.028~0.158 | 0.265 | 0.020 | -0.015~0.054 | |
| iPTH | 0.026 | -0.056 | -0.105~-0.007 | 0.934 | 0.001 | -0.022~0.024 | |
| Serum Calcium | 0.178 | -10.382 | -25.502~4.739 | 0.167 | 4.810 | -2.056~11.677 | |
| Serum Phosphor | 0.483 | 4.387 | -7.897~16.671 | 0.142 | 5.345 | -1.835~12.525 | |
| Serum Creatinine | 0.941 | -0.197 | -5.441~5.047 | 0.887 | -0.217 | -3.238~2.804 | |
| FGF23 | 0.006 | 0.276 | 0.080~0.473 | 0.244 | 0.034 | -0.024~0.092 | |
| OPG | 0.274 | -0.821 | -2.296~0.654 | 0.242 | -0.262 | -0.705~0.181 | |
| ALP | 0.585 | -0.022 | -0.103~0.058 | 0.493 | -0.013 | -0.051~0.025 | |
| Sclerostin | 0.296 | -0.053 | -0.154~0.047 | 0.717 | 0.011 | -0.050~0.072 |
Vitamin D sufficient group: 25(OH)D≥30ng/mL; vitamin D deficient group: 25(OH)D<30ng/mL.
25(OH)D, 25-hydroxy-vitamin D; 1,25(OH)2D, 1,25-dihydroxyvitamin D; iPTH, intact parathyroid hormone; FGF23, Fibroblast Growth Factor 23 receptor; OPG, osteoprotegerin; ALP, alkaline phosphatas.
Coefficients B: unstandardized coefficients B.
95%CI: 95% Confidence interval for B.
Parameters recognized in the literature as affecting PTH concentration (age, serum calcium, serum phosphor, creatinine, FGF23, OPG, ALP, and sclerostin) were introduced into the multivariate linear regression model.