PFIC
|
Progressive familial cholestasis |
BRIC
|
Benign recurrent intrahepatic cholestasis |
ICP
|
Intrahepatic cholestasis pregnancy |
NAFLD
|
Nonalcoholic fatty liver disease |
PBC
|
Primary biliary cirrhosis |
PSC
|
Primary sclerosing cholangitis |
ESLD
|
End-stage liver disease |
GGT
|
Gamma-glutamyltransferase |
TJP2
|
Tight junction protein 2 |
FXR
|
Farnesoid X receptor |
ATP8B1
|
ATPase class I type 8B member 1 |
PE
|
Phosphatidylethanolamine |
LDLR
|
Levels of low-density lipoprotein receptor |
ASBT
|
Apical sodium-dependent bile acid transporter |
CFTR
|
Cystic fibrosis transmembrane conductance regulator |
4-PB
|
4-phenylbutyrate |
SAHA
|
suberoylanilide hydroxamic acid |
NB-DNJ
|
N-butyl deoxynojirimycin |
PS
|
Phosphatidylserine |
CDC42
|
Control protein 42 homologous |
CDC50A
|
Cell cycle control protein 50A |
UDCA
|
Ursodeoxycholic acid |
PEBD
|
Partial external bile duct transfer |
PIBD
|
Partial internal bile duct shunt |
IE
|
Ileal rejection |
HMDMs
|
Human monocyte-derived macrophages |
AFP
|
Alpha-fetoprotein |
MDR1
|
Multidrug transporter P-glycoprotein |
RXRα
|
Retinoid X receptor alpha |
FXRE
|
FXR response element |
LKB1
|
liver kinase B1 |
AMPK
|
AMP-activated protein kinase |
LRH-1
|
Liver receptor homolog |
NCOA6
|
nuclear receptor coactivator 6 |
ERAD
|
Endoplasmic reticulum degradation-associated structure |
HAX-1
|
HCLS1-associated protein X-1 |
EPS15
|
Epidermal growth factor receptor pathway substrate 15 |
AP-2
|
Adaptor protein-2 |
ESE
|
Exonic splicing enhancers |
ESS
|
Exonic splicing silencer |
QSAR
|
Quantitative Structure-Activity Relationship |
AIBD
|
Autoimmune BSEP disease |
IF
|
Immunofluorescence |
IHC
|
Immunohistochemistry |
MDR3
|
Multidrug resistance protein 3 |
LPAC
|
Low phospholipid-associated cholelithiasis |
DILI
|
Drug-induced liver injury |
CMV
|
Canalicular membrane vesicles |
AIBD
|
Autoimmune BSEP disease |
PC
|
Phosphatidylcholine |
NBD
|
Nucleotide binding domain |
AAV
|
Adeno-associated virus |
rAAV
|
Recombinant adeno-associated virus |
MARS
|
Molecular adsorbent recirculation system |
CLDN1
|
Claudin domain-containing protein 1 |
CARM1
|
Histone methyltransferase Histone-arginine methyltransferase CARM1 |
OSTα
|
Organic solute transporter subunit alpha |
USP53
|
Ubiquitin specific peptidase 53 |
KIF12
|
Kinesin-related protein 12 |
ANCHR
|
Abscission/NoCut checkpoint regulator |
ICBs
|
Intercellular bridges |
CHMP4C
|
Charged multivesicular body protein 4c |
DPM
|
Ductal plate malformations |
EVS
|
Extracellular vehicles |
LSCEVS
|
liver stem cell-derived EVS |
MYO5B
|
myosin VB |
MVID
|
Microvillus inclusion body disease |
SEMA7A
|
Semaphorin 7A |
ARC
|
Arthrogryposis-Renal Dysfunction-Cholestasis |
JAG1
|
Protein jagged-1 |
NOTCH2
|
Neurogenic locus notch homolog protein 2 |
PEBD
|
Partial external bile duct drainage |
UGT1A1
|
UDP-glucuronosyltransferase 1A1 |
DJs
|
Dubin -Johnson syndrome |
NSC
|
Neonatal sclerosing cholangitis |
BASM
|
Biliary Atresia Splenic Malformation |
HCV
|
Hepatitis C virus |
IPD
|
Individual patient data |
GWAS
|
Genome-wide association studies |
PTPN22
|
Tyrosine-protein phosphatase non-receptor type 22 |
HIHC
|
Hereditary Intrahepatic Cholestasis |