Table 1.
Demographic and insult severity data for piglets subjected to a hypoxic-ischemic insult (HI) with or without therapeutic hypothermia (HI + TH) and controls.
| Gender (m/f) | |
| Control | 3/2 |
| HI | 4/5 |
| HI + TH | 4/4 |
| Weight (kg) | |
| Control | 1.50 (1.25–1.70) |
| HI | 1.80 (1.60–1.90) |
| HI + TH | 1.60 (1.50–1.85) |
| Time < 7 µV aEEG (min) | |
| HI | 34.6 (27.7–37.1) |
| HI + TH | 40.5 (23.0–42.2) |
| Time MABP < 70% of baseline (min) | |
| HI | 19.3 (5.0–22.1) |
| HI + TH | 18.0 (12.3–36.3) |
| Norepinephrine infusion (µg/kg/min) | |
| Control | 0/5 (0.00 (0.00–0.00)) |
| HI | 8/9 (0.49 (0.18–0.55)) a |
| HI + TH | 5/8 (0.45 (0.16–0.69)) a |
The number of animals in each group who received norepinephrine infusion is reported. The infusion rate was calculated for each hour and averaged over the 24-h observation period. Data are median with interquartile range. Values with significant in-group differences are bold.
aEEG, amplitude integrated electroencephalography; MABP, mean arterial blood pressure.
a
Indicates significance vs. controls.