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. 2023 Jun 14;1(2):16. doi: 10.1007/s44254-023-00018-2

Table 2.

Analgesics and their cytochrome P450 (CYP) and P-glycoproten (P-gp) metabolic pathways

graphic file with name 44254_2023_18_Tab2_HTML.jpg

Major pathway Inline graphic ; Minor pathway Inline graphic ; Active metabolite Inline graphic

Reproduced from Rollason V, Lloret-Linares C, Lorenzini KI, et al. Evaluation of phenotypic and genotypic variations of drug metabolising enzymes and transporters in chronic pain patients facing adverse drug reactions or non-response to analgesics: A retrospective study. J Pers Med. 2020; 10:198. doi: 10.3390/jpm10040198 [16], an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/)