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. 2023 Jun 14;37(7):1521–1529. doi: 10.1038/s41375-023-01936-7

Table 3.

Overview of TEAEs.

n (%) All
(n = 73)
Any TEAE 73 (100)
Grade ≥3 TEAEs 58 (79.5)
Treatment-emergent SAEs 39 (53.4)
Drug-related treatment-emergent SAEs 22 (30.1)
TEAEs leading to deatha 7 (9.6)
TEAEs leading to permanent discontinuation of study treatment 14 (19.2)
TEAEs leading to premature study drug discontinuation 24 (32.9)
  Bortezomib 13 (17.8)
  Lenalidomide 11 (15.1)
  Dexamethasone 4 (5.5)

aTEAEs leading to death included listeremia (n = 1), progressive disease (n = 1), metastatic breast cancer (n = 1), metastatic melanoma (n = 1), COVID-19 (n = 2), diverticulitis (n = 1)

SAE, serious adverse event; TEAE, treatment-emergent adverse event.