Table 3.
HZ vaccine recommendations in Southeast Asia
| Country | Recommendations for HZ vaccination | Reference for the indications |
|---|---|---|
| Indonesia |
Live attenuated zoster vaccine 1 dose for all individuals > 50 years Contraindicated for primary and secondary immunocompromised individuals (e.g., receiving chemotherapy, high-dose prednisone, or other immunomodulator medications), patients with HIV and CD4 < 200 cells/mm3, and pregnant individuals |
Adult Immunization Task Force, Indonesia Society of Internal Medicine (PAPDI) 2022 [117] |
| Malaysia |
Recombinant zoster vaccine Individuals > 50 years with a history of varicella Zoster vaccine may be given regardless of whether or not they have had prior HZ infection Healthcare workers > 50 years as they are at a higher risk of exposure to VZV spread varicella to patients |
Guideline for Adult Immunization (Malaysia Society of Infectious Diseases and Chemotherapy), 2020 [118] |
| Philippines |
Live attenuated vaccine: immunocompetent ≥ 60 years Adjuvanted recombinant vaccine: immunocompetent ≥ 50 years |
Philippine Guidelines on Periodic Health Examination 2021 (PHEX unpublished manuscript) [119] |
| Singapore |
Live attenuated vaccine: individuals > 50 years Contraindicated for individuals who have experienced anaphylaxis to any vaccine component (including neomycin and gelatin) or a previous dose; and immunocompromised individuals (except patients with leukemia in remission and who have not received chemotherapy or radiation for ≥ 3 months) |
Handbook on Adult Vaccination in Singapore 2020 [120] |
| Thailand | 1 dose of live-attenuated zoster vaccine in individuals aged > 60 | Recommended Adult and Elderly Immunization Schedule (IDAT) 2018 [121] |
| Vietnam | Elderly and immunocompromised adults | No local recommendations to date |
HZ herpes zoster, IDAT Infectious Disease Association of Thailand, PAPDI Perhimpunan Dokter Spesialis Penyakit Dalam Indonesia, PHEX Philippine Guidelines on Periodic Health Examination