TABLE 1.
Sex characteristics of the 281 clinical drug trials published in Clinical Pharmacology and Therapeutics or Clinical and Translational Science in 2000–2001 or 2020–2021.
| 2000–2001 | 2020–2021 | |||
|---|---|---|---|---|
| n | % | n | % | |
| Research participants | ||||
| All included articles | 6779 | 100.0 | 10,860 | 100.0 |
| Female | 2374 | 35.0 | 3936 | 36.2 |
| Male | 4405 | 65.0 | 6924 | 63.8 |
| Subgroup analysis a | 6204 | 100.0 | 10,390 | 100 |
| Female | 2374 | 38.3 | 3936 | 37.8 |
| Male | 3830 | 61.7 | 6454 | 62.2 |
| Authors b | ||||
| All authors | 943 | 100.0 | 1267 | 100.0 |
| Female | 243 | 25.8 | 489 | 38.6 |
| Male | 685 | 72.6 | 699 | 55.2 |
| First author | 151 | 100.0 | 130 | 100.0 |
| Female | 47 | 31.1 | 49 | 37.7 |
| Male | 100 | 66.2 | 77 | 59.2 |
| Last author | 151 | 100.0 | 130 | 100.0 |
| Female | 19 | 12.6 | 37 | 28.5 |
| Male | 131 | 86.8 | 91 | 70.0 |
Abbreviation: n, number of individuals.
a
Subgroup analysis: the sex distribution for 222 articles not having female sex as an exclusion criterion.
b
The remaining proportion not accounted for is due to unknown sex of the author.