TABLE 1.
Characteristics of the sample, stratified into survivor and non‐survivor.
| Total n = 171 | Survivor n = 142 (83%) | Non‐survivor n = 29 (17%) | p‐value | |
|---|---|---|---|---|
| Age in year, mean (SD) | 65.9 (11.8) | 73 (10.6) | 58.9 (13.1) | ˂0.0001 |
| Age group, n (%) | ˂0.0001 | |||
| ˂65 years | 105 (61.4) | 99 (69.7) | 6 (20.7) | |
| ≥ 65 years | 66 (38.6) | 43 (30.3) | 23 (79.3) | |
| Sex, n (%) | 0.944 | |||
| Males | 113 (66.1) | 94 (66.2) | 19 (66.5) | |
| Females | 58 (33.9) | 48 (33.8) | 10 (34.5) | |
| The anticoagulant used, n (%) | 0.3719 | |||
| Heparin | 16 (9.5) | 12 (8.6) | 4 (13.8) | |
| Enoxaparin | 133 (78.7) | 113 (80.7) | 20 (69) | |
| Both/rivaroxaban | 20 (11.8) | 15 (10.7) | 5 (17.2) | |
| Anticoagulant dose, n (%) | 0.810 | |||
| Prophylactic | 56 (32.9) | 47 (33.3) | 9 (31) | |
| Therapeutic | 114 (67.1) | 94 (66.7) | 20 (69) | |
| Respiratory rate (cycles/min), median (IRQ) | 21 (15–22) | 18 (15–20) | 20 (15–25) | |
| Heart rate (beats/min), mean (SD) | 87.1 (13.8) | 83.1 (13.4) | 91.1 (14.3) | |
| Systolic BP (mm Hg), mean (SD) | 127.7 (20.1) | 126.3 (18.2) | 129.2 (22.1) | 0.447 |
| Systolic BP (mm Hg), mean (SD) | 73.5 (10.8) | 74.1 (10.9) | 73.0 (10.8) | 0.612 |
| SOFA score, median (IRQ) | 3 (2–9) | 2 (2–11) | 3 (2–7) | ˂0.0001 |
| Padua prediction score, n (%) | ˂0.0001 | |||
| 4 or less | 107 (64.1) | 99 (71.7) | 8 (27.6) | |
| More than 4 | 60 (35.9) | 39 (28.3) | 21 (72.4) | |
| FO2, median (IRQ) | 30 (10.5–34) | 28 (0–32) | 32 (21–36) | ˂0.0001 |
| Temperature (°C), median (IRQ) | 37 (36–37) | 37 (36–37) | 37 (36–37) | ˂0.0001 |
| Ventilator used, n (%) | ˂0.0001 | |||
| No | 148 (87.6) | 133 (95) | 15 (51.7) | |
| Yes | 21 (12.4) | 7 (5) | 14 (48.3) | |
| Comorbidities, n (%) | 0.282 | |||
| 0 or 1 | 43 (25.2) | 38 (26.8) | 5 (17.2) | |
| ≥2 | 128 (74.8) | 104 (73.2) | 24 (82.8) | |
| Creatinine clearance, median (IRQ) | 54.4 (7.2–72.3) | 82.6 (6.2–105.6) | 26.2 (8.8–39.1) | ˂0.0001 |
| Creatinine, mean (SD) | 1.7 (1.6) | 1.1 (1.5) | 2.4 (1.8) | 0.001 |
| Last platelets, mean (SD) | 226.5 (109.1) | 174.9 (114.1) | 278.1 (104.2) | ˂0.0001 |
| Last lactic acid, median (IRQ) | 2.2 (0.4–3.2) | 1.4 (0.7–2) | 3 (0.9–4.5) | ˂0.0001 |
| Last iron, mean (SD) | 71.4 (37.9) | 57.6 (27.5) | 85.3 (48.4) | 0.045 |
| Ferritin level, median (IRQ) | 807 (28–1620) | 535 (10–1098) | 1079 (46–2143) | ˂0.0001 |
| Baseline D‐dimer, median (IRQ) | 0.7 (0–1.1) | 0.5 (0–1) | 0.9 (0–1.3) | ˂0.0001 |
| Hospital length of stay, median (IRQ) | 15 (4–20) | 12 (2–19) | 18 (6–21) | ˂0.0001 |
| Length of stay in ICU, median (IRQ) | 6 (0.7–10) | 4 (0.5–7) | 8 (1–13) | ˂0.0001 |
Abbreviations: BP, blood pressure; ICU, intensive care unit; IRQ, interquartile range; SD, standard deviation.