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. 2023 Jun 13;10(5):e200135. doi: 10.1212/NXI.0000000000200135

Figure 1. Overview of CXCL13 and sCD27 Concentrations in CSF From Patients and Controls.

Figure 1

The figure shows an overview of CXCL13 (A) and sCD27 (B) concentrations in CSF of healthy volunteers (n = 32) without neurologic disease and patients with relapsing-remitting MS undergoing autologous hematopoietic stem cell transplantation. A vertical dashed line separates the controls from the patients. Patients were followed with repeated lumbar punctures for up to 5 years after autologous hematopoietic stem cell transplantation (n = 45 at baseline; n = 44 at 1 year; n = 31 at 2 years; n = 3 at 3 years; n = 1 at 4 years; and n = 10 at 5 years). Median values are highlighted by horizontal lines. Active disease (a clinical relapse or gadolinium-enhancing lesions on MRI) at the time when the sample was taken is denoted by red color. Two patients had a clinical relapse in conjunction to a follow-up visit; these patients are represented by triangles (1 filled and 1 open).