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. 2023 May 31;24(6):2766–2776. doi: 10.1021/acs.biomac.3c00178

Figure 6.

Figure 6

Representative live-cell spinning disk confocal microscopy images showing that V-SNAs retain enhanced cellular uptake following prolonged incubation in FBS. (a) Qβ-VLPs were pretreated with (top) 1xPBS or (bottom) 20% FBS for 16 h at 37 °C, after which C166 cells were dosed with 5 nM VLPs diluted in OptiMEM for 90 min. (b) Mean fluorescence intensity per cell from data such as in (a). Statistics were performed in Prism by two-way ANOVA with Tukey’s multiple comparison test; *** = p ≤ 0.001; ** = p ≤ 0.01; * = p ≤ 0.05.