Table 2.

Univariate and Multivariate analysis of risk factors for major bleeding complications

Characteristics	No. of events	Person-years of follow-up	Incidence rate/100 person-years	Crude RR	95% CI	p-value	Adjusted RR	95% CI		p-value
Age group (years)
< 60	2	131.13	1.53	1.00
60–69	6	186.66	3.21	2.50	0.41–1.17	0.378	2.75	0.51–14.68		0.237
70–79	9	228.94	3.93	2.81	0.61–13.20	0.186	4.30	0.83–22.35		0.082
≥ 80	5	125.19	3.99	2.29	0.44–11.80	0.322	3.08	0.50–19.00		0.225
Gender
Male	11	296.78	3.76	1.00
Female	11	375.14	2.93	0.73	0.32–1.68	0.454	0.72	0.30–1.69		0.448
BMI (kg/m2)
18.50–22.99	10	177.18	5.64	1.00
< 18.50	1	49.23	2.31	0.31	0.40–2.42	0.264	0.34	0.04–2.70		0.308
23.00–24.99	1	112.26	0.90	0.19	0.20–1.45	0.109	0.24	0.03–1.93		0.181
25.00-29.99	7	184.24	3.80	0.69	0.26–1.80	0.443	0.71	0.26–1.93		0.501
≥ 30.00	3	120.73	2.48	0.54	0.15–1.95	0.344	0.68	0.17–2.72		0.586
Hypertension
No	11	178.75	6.15	1.00
Yes	11	492.93	2.23	0.50	0.22–1.16	0.109	0.40	0.17–0.95		0.037
Amiodarone prescription
No	20	662.75	3.18	1.00
Yes	2	9.17	21.81	4.69	1.10–2.50	0.037	5.11	1.08–24.15		0.039
Propranolol prescription
No	13	533.71	2.44	1.00
Yes	9	138.21	6.51	2.88	1.23–6.73	0.015	2.86	1.19–6.83		0.018

*Data were adjusted for age, gender, BMI, comorbidities and medication, RR; Relative risk, 95% CI; 95% confidence interval, BMI; body mass index, kg/m2; kilogram per square meter