Table 4.
Antimicrobial screening results of pefloxacin and its complexes evaluated by the mean inhibition zone in mm
| Compound | Gram negative bacteria | Gram positive bacteria | Fungi | |||
|---|---|---|---|---|---|---|
| Escherichia coli | Pseudomonas aeruginosa | Streptococcus pneumonia | Bacillus subtilis | Aspergillus fumigatus | Candida albicans | |
| Pefloxacin mesylate dihydrate | 22.4 ± 0.63 | nda | 21.2 ± 0.63 | 23.2 ± 0.63 | nda | nda |
| [Cu(Pf)2(H2O)2].3H2O | 22.1 ± 0.72 | nda | 24.3 ± 1.2 | 25.4 ± 0.58 | 18.3 ± 0.63 | nda |
| [Cu(HPf)(bipy)(NO3)]NO3.2H2O | 21.6 ± 0.63 | nda | 19.6 ± 1.2 | 20.8 ± 0.63 | nda | nda |
| [Cu(HPf)(phen)(NO3)]NO3.2H2O | 20.3 ± 0.63 | nda | 18.3 ± 0.58 | 18.9 ± 0.25 | nda | nda |
| Amphotericin B | 23.7 ± 0.1 | 25.4 ± 0.1 | ||||
| Ampicillin | 23.8 ± 0.2 | 32.4 ± 0.3 | ||||
| Gentamicin | 19.9 ± 0.3 | 17.3 ± 0.1 | ||||
nda = no detected activity