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. 2023 Jun 14;2023(6):CD001506. doi: 10.1002/14651858.CD001506.pub5

Palacio 2014.

Methods Open‐label RCT.
Parallel assignment.
Location: 2 centres in Argentina.
Duration: 24 weeks.
Participants 27 children aged 3 to 6 years with CF. 21 completed trial.
Interventions Intervention 1: HS 7% nebulised 2x daily.
Control: IS 0.9%, nebulised 2x daily.
Salbutamol given prior to each dose.
Outcomes Primary outcome
Lung function
Secondary outcomes
Respiratory symptoms
Anthropometric measures
New isolation of Pseudomonas aeruginosa
Rate of exacerbations
AEs
Adherence
Notes We are waiting for further data to judge whether this should be included.