. Author manuscript; available in PMC: 2023 Sep 1.

Published in final edited form as: Ann Allergy Asthma Immunol. 2022 May 18;129(3):327–334. doi: 10.1016/j.anai.2022.05.005

Table 2.

Adjusted Odds Ratios and 95% CI for Association of Past Asthma and Current Childhood and Adult Onsets of Asthma vs no Asthma With Comorbidities, NHANES 2001–2018 (N = 27,437)

Comorbidities	Past and current asthma vs no asthma			Current asthma vs past asthma

	Past asthma	Current asthma

		Childhood-onset	Adult-onset	Childhood-onset	Adult-onset

Obesity	1.14 (0.95–1.37)	1.35 (1.09–1.67) ^a	1.93 (1.65–2.26) ^b	1.16 (0.88–1.53)	1.63 (1.31–2.04) ^b
Blood total cholesterol
Borderline high	0.92 (0.76–1.12)	0.79 (0.62–1.02)	0.99 (0.84–1.17)	0.65 (0.42–1.01)	1.10 (0.80–1.52)
High	1.07 (0.84–1.36)	0.68 (0.47–1.00)	1.16 (0.95–1.42)	0.85 (0.60–1.19)	1.11 (0.88–1.41)
Serum LDL cholesterol
Borderline high	1.13 (0.88–1.46)	0.89 (0.58–1.37)	0.97 (0.76–1.24)	0.56 (0.27–1.16)	1.14 (0.66–1.97)
High	1.04 (0.67–1.61)	0.55 (0.32–0.95) ^c	1.20 (0.89–1.61)	0.77 (0.46–1.29)	0.88 (0.60–1.28)
Blood triglycerides
Borderline high	0.93 (0.74–1.19)	0.77 (0.57–1.05)	1.28 (1.01–1.63) ^c	0.81 (0.57–1.17)	1.38 (0.99–1.93)
High	1.00 (0.80–1.25)	1.18 (0.94–1.48)	1.37 (1.14–1.65) ^b	1.15 (0.84–1.58)	1.38 (1.02–1.85) ^c
Diabetes	1.24 (0.98–1.56)	1.36 (1.03–1.78) ^c	1.62 (1.37–1.91) ^b	0.99 (0.71–1.37)	1.20 (0.94–1.54)
Hypertension	1.20 (1.03–1.41) ^c	1.48 (1.18–1.85) ^a	1.59 (1.36–1.87) ^b	1.21 (0.90–1.61)	1.32 (1.06–1.65) ^c
CVD	1.33 (1.06–1.68) ^c	2.42 (1.81–3.24) ^b	2.55 (2.14–3.03) ^b	1.63 (1.18–2.26) ^a	1.86 (1.40–2.48) ^b
CKD	1.01 (0.75–1.37)	1.37 (0.94–2.01)	1.17 (0.94–1.45)	1.35 (0.82–2.22)	1.20 (0.86–1.66)
Arthritis
Rheumatoid arthritis	1.18 (0.86–1.62)	3.11 (2.24–4.31) ^b	2.38 (1.90–2.99) ^b	2.40 (1.49–3.86) ^b	1.93 (1.36–2.73) ^b
Osteoarthritis	1.45 (1.13–1.85) ^a	1.58 (1.14–2.19) ^a	2.44 (2.00–2.98) ^b	1.04 (0.67–1.60)	1.57 (1.17–2.11) ^a
Other/unknown	1.31 (1.04–1.66) ^c	1.76 (1.34–2.31) ^b	2.40 (1.93–3.00) ^b	1.29 (0.89–1.88)	1.84 (1.36–2.48) ^b
Cancer/history of cancer	1.24 (0.97–1.57)	1.48 (1.04–2.10) ^c	1.44 (1.20–1.73) ^b	1.16 (0.78–1.70)	1.14 (0.85–1.53)
Anemia	1.15 (0.89–1.50)	1.29 (1.01–1.64) ^c	1.48 (1.22–1.80) ^b	1.11 (0.76–1.61)	1.29 (0.94–1.79)
Depression	1.29 (0.94–1.76)	1.98 (1.33–2.96) ^a	2.19 (1.73–2.77) ^b	1.53 (0.96–2.44)	1.74 (1.24–2.43) ^a
Airflow obstruction	1.74 (1.25–2.43) ^a	2.94 (1.64–5.26) ^b	2.51 (1.82–3.45) ^b	1.67 (0.95–2.93)	1.56 (1.01–2.41) ^c
COPD	1.92 (1.22–3.01) ^a	1.77 (0.92–3.41)	0.99 (0.61–1.63)	0.96 (0.48–1.92)	0.57 (0.30–1.09)

Abbreviations: CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; CVD, cardiovascular disease; LDL, low density lipoprotein; NHANES, National Health and Nutrition Examination Survey; PIR, poverty income ratio.

NOTE. All models were adjusted for age, sex, race and ethnicity, poverty income ratio, pack-years of cigarette smoking, health insurance, and NHANES survey cycle.

Bold indicates significant results.

P < .01.

P < .001.

P < .05.