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. 2023 Jun 14;25(6):euad149. doi: 10.1093/europace/euad149

Table 2.

Association of BMP10 concentration and AF recurrence

BMP10 Model 1: unadjusted Model 2: age- and sex-adjusted Model 3: multivariable adjusteda
HR (95% CI) HR (95% CI) HR (95% CI)
Continuousb 2.28 (1.43; 3.62), P < 0.001 2.08 (1.23; 3.52), P = 0.006 1.98 (1.14; 3.42), P = 0.01
Quartile I Reference Reference Reference
Quartile II 1.05 (0.77; 1.43) 1.02 (0.75; 1.40) 1.00 (0.73; 1.37)
Quartile III 1.13 (0.84; 1.53) 1.10 (0.81; 1.49) 1.07 (0.78; 1.46)
Quartile IV 1.58 (1.19; 2.10) 1.50 (1.10; 2.06) 1.46 (1.06; 2.02)
P for linear trend 0.002 0.01 0.02
P for quadratic trend 0.17 0.17 0.14

AF, atrial fibrillation; BMP10, bone morphogenetic protein 10; CI, confidence interval; HR, hazard ratio.

a

Model 3 adjusted for age, sex, body mass index, history of coronary artery disease, hypertension, heart failure, diabetes, stroke, and renal failure.

b

BMP10 was log-transformed. Model 1 & model 2: n = 1112; model 3: n = 1101.