Table 2.
BMP10 | Model 1: unadjusted | Model 2: age- and sex-adjusted | Model 3: multivariable adjusteda |
---|---|---|---|
HR (95% CI) | HR (95% CI) | HR (95% CI) | |
Continuousb | 2.28 (1.43; 3.62), P < 0.001 | 2.08 (1.23; 3.52), P = 0.006 | 1.98 (1.14; 3.42), P = 0.01 |
Quartile I | Reference | Reference | Reference |
Quartile II | 1.05 (0.77; 1.43) | 1.02 (0.75; 1.40) | 1.00 (0.73; 1.37) |
Quartile III | 1.13 (0.84; 1.53) | 1.10 (0.81; 1.49) | 1.07 (0.78; 1.46) |
Quartile IV | 1.58 (1.19; 2.10) | 1.50 (1.10; 2.06) | 1.46 (1.06; 2.02) |
P for linear trend | 0.002 | 0.01 | 0.02 |
P for quadratic trend | 0.17 | 0.17 | 0.14 |
AF, atrial fibrillation; BMP10, bone morphogenetic protein 10; CI, confidence interval; HR, hazard ratio.
Model 3 adjusted for age, sex, body mass index, history of coronary artery disease, hypertension, heart failure, diabetes, stroke, and renal failure.
BMP10 was log-transformed. Model 1 & model 2: n = 1112; model 3: n = 1101.