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. 2023 May 21;20(7):969–975. doi: 10.7150/ijms.84364

Table 3.

Odds ratio (OR) and 95% confidence interval (CI) of clinical status and WWOX rs11545028 genotypic frequencies in 578 patients with prostate cancer.

Variable Genotypic frequencies
rs11545028 CC (N=341) CT+TT (N=237) OR (95% CI) p value
PSA at diagnosis (ng/mL)
≤ 10 156 (45.7 %) 114 (48.1 %) 1.00 p=0.577
> 10 185 (54.3 %) 123 (51.9 %) 0.910 (0.653-1.268)
Pathologic Gleason grade group
1+2+3 289 (84.8%) 194 (81.9%) 1.00 p=0.356
4+5 52 (15.2%) 43 (18.1%) 1.232 (0.791-1.919)
Clinical T stage
1+2 298 (87.4%) 202 (85.2%) 1.00 p=0.455
3+4 43 (12.6%) 35 (14.8%) 1.201 (0.743-1.942)
Clinical N stage
N0 333 (97.7 %) 232 (97.9 %) 1.00 p=0.851
N1 8 (2.3 %) 5 (2.1 %) 0.897 (0.290-2.777)
Clinical M stage
M0 336 (98.5 %) 232 (97.9 %) 1.00 p=0.560
M1 5 (1.5 %) 5 (2.1 %) 1.448 (0.415-5.059)
Pathologic T stage
2 186 (54.5%) 120 (50.6%) 1.00 p=0.354
3+4 155 (45.5%) 117 (49.4%) 1.170 (0.839-1.631)
Pathologic N stage
N0 315 (92.4%) 214 (90.3%) 1.00 p=0.377
N1 26 (7.6%) 23 (9.7%) 1.302 (0.724-2.343)
Seminal vesicle invasion
No 276 (80.9%) 175 (73.8%) 1.00 p=0.043*
Yes 65 (19.1%) 62 (26.2%) 1.504 (1.012-2.236)
Perineural invasion
No 92 (27.0%) 63 (26.6%) 1.00 p=0.916
Yes 249 (73.0%) 174 (73.4%) 1.020 (0.702-1.484)
Lymphovascular invasion
No 284 (83.3%) 197 (83.1%) 1.00 p=0.959
Yes 57 (16.7%) 40 (16.9%) 1.012 (0.649-1.576)
D'Amico classification
Low/Intermediate risk 161 (47.2%) 118 (49.8%) 1.00 p=0.542
High risk 180 (52.8%) 119 (50.2%) 0.902 (0.647-1.257)

The ORs with analyzed by their 95% CIs were estimated by logistic regression models. * p value < 0.05 as statistically significant.