Table 3.
Associations between DPY30 expression and clinicopathological characteristics of CRC patients.
| Characteristics | Variable | N | DPY30 | X2 | P | |
|---|---|---|---|---|---|---|
| Low | High | |||||
| Age | ||||||
| < 60 | 28 | 11 | 17 | 0.079771 | 0.7776 | |
| ≥ 60 | 66 | 28 | 38 | |||
| Gender | ||||||
| Male | 48 | 19 | 29 | 0.14681 | 0.7016 | |
| Female | 46 | 20 | 26 | |||
| Pathological grading | ||||||
| Ⅰ | 3 | 0 | 3 | 125 | 0.0348* | |
| Ⅰ-Ⅱ | 16 | 6 | 10 | |||
| II | 60 | 22 | 38 | |||
| II-III | 9 | 5 | 4 | |||
| III | 5 | 5 | 0 | |||
| Ⅲ-Ⅳ | 1 | 1 | 0 | |||
| Tumor size | ||||||
| d ≤ 4 | 28 | 12 | 16 | 7.9052 | 0.0192* | |
| 4 < d ≤ 6 | 40 | 19 | 21 | |||
| d > 6 | 20 | 2 | 17 | |||
| T category | ||||||
| T1 | 1 | 0 | 1 | 2.053 | 0.5622 | |
| T2 | 10 | 4 | 6 | |||
| T3 | 51 | 19 | 32 | |||
| T4 | 32 | 16 | 16 | |||
| N stage | ||||||
| N0 | 60 | 24 | 36 | 0.15212 | 0.9268 | |
| N1 | 25 | 11 | 14 | |||
| N2 | 9 | 4 | 5 | |||
| M stage | ||||||
| M0 | 89 | 37 | 52 | 0.0048251 | 0.9446 | |
| M1 | 5 | 2 | 3 | |||
| TNM stage (AJCC) | ||||||
| Stage I | 10 | 7 | 3 | 8.5173 | 0.0365* | |
| Stage II | 48 | 19 | 29 | |||
| Stage III | 31 | 13 | 16 | |||
| Stage IV | 5 | 0 | 7 | |||
| Tumor location | ||||||
| Ascending colon | 34 | 18 | 16 | 13.525 | 0.019* | |
| Colon hepatic flexure | 6 | 4 | 2 | |||
| Transverse colon | 5 | 4 | 1 | |||
| Colon splenic flexure | 3 | 1 | 2 | |||
| Descending colon | 8 | 2 | 6 | |||
| Sigmoidal and rectum | 36 | 8 | 29 | |||
| The pathologic types | ||||||
| Tubular adenocarcinoma | 7 | 2 | 5 | 2.6843 | 0.4429 | |
| Adenocarcinoma | 83 | 34 | 49 | |||
| Mucous adenocarcinoma | 3 | 2 | 1 | |||
| Signet ring cell carcinoma | 1 | 1 | 0 | |||
| Positive lymph nodes | ||||||
| n ≤ 3 | 84 | 35 | 49 | 2.8353 | 0.4178 | |
| 3< n ≤ 7 | 7 | 4 | 3 | |||
| n > 7 | 2 | 0 | 2 | |||
*Indicates statistical significance.