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. 2023 May 29;19(9):2803–2816. doi: 10.7150/ijbs.81726

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PBX1 is downregulated in NSCLC and inhibits NSCLC cell proliferation and migration. (A) NSCLC (C) and adjacent normal (N) tissues were collected for IB assays. (B) Statistical analyses of PBX1 in NSCLC tissues. (C) Representative analysis of PBX1 expression in NSCLC by immunohistochemical analysis. (D) Overall survival analysis of NSCLC patients in terms of PBX1 expression. Data was retrieved from Kaplan-Meier Plotter. (E-F) A549 and H226 cell lines were overexpressed with PBX1 or were knocked down for PBX1. Cells were then subjected to EdU staining (E) or transwell assays to evaluate cell migration (F).