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. 2023 May 30;13:1196967. doi: 10.3389/fcimb.2023.1196967

Table 5.

Top 15 high-cited articles related to gut microbiome and metabolism.

Rank Author Article Title Source Title Citations Year Document Type DOI
1 Wang, ZN et al. Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease NATURE 3224 2011 Article 10.1038/nature09922
2 Hsiao, EY et al. Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders CELL 1880 2013 Article 10.1016/j.cell.2013.11.024
3 Wikoff, WR et al. Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites PNAS 1649 2009 Article 10.1073/pnas.0812874106
4 Markle, JGM et al. Sex Differences in the Gut Microbiome Drive Hormone-Dependent Regulation of Autoimmunity SCIENCE 1144 2013 Article 10.1126/science.1233521
5 Johnson, CH et al. Metabolomics: beyond biomarkers and towards mechanisms NATURE REVIEWS MOLECULAR CELL BIOLOGY 1073 2016 Review 10.1038/nrm.2016.25
6 Kostic, AD et al. The Microbiome in Inflammatory Bowel Disease: Current Status and the Future Ahead GASTROENTEROLOGY 1024 2014 Article 10.1053/j.gastro.2014.02.009
7 Franceschi, C et al. Inflammaging: a new immune-metabolic viewpoint for age-related diseases NATURE REVIEWS ENDOCRINOLOGY 925 2018 Review 10.1038/s41574-018-0059-4
8 Plovier, H et al. A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice NATURE MEDICINE 922 2017 Article 10.1038/nm.4236
9 Dumas, ME et al. Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice PNAS 807 2006 Article 10.1073/pnas.0601056103
10 Li, M et al. Symbiotic gut microbes modulate human metabolic phenotypes PNAS 802 2008 Article 10.1073/pnas.0712038105
11 Fan, Yet al. Gut microbiota in human metabolic health and disease NATURE REVIEWS MICROBIOLOGY 754 2021 Review 10.1038/s41579-020-0433-9
12 Li, J et al. Gut microbiota dysbiosis contributes to the development of hypertension MICROBIOME 722 2017 Article 10.1186/s40168-016-0222-x
13 De Filippis, Fet al. High-level adherence to a Mediterranean diet beneficially impacts the gut microbiota and associated metabolome GUT 712 2016 Article 10.1136/gutjnl-2015-309957
14 Knight, R et al. Best practices for analysing microbiomes NATURE REVIEWS MICROBIOLOGY 674 2018 Review 10.1038/s41579-018-0029-9
15 Nicholson, JK et al. Gut microorganisms, mammalian metabolism and personalized health care NATURE REVIEWS MICROBIOLOGY 670 2005 Review 10.1038/nrmicro1152