Table 1. Baseline demographic characteristics according to leaflet position and mechanism of valve expansion.
| Characteristic | Overall (n=1,378) | Supra-annular valve (n=920) | Intra-annular valve (n=458) | p-value (supra-annular vs intra-annular) | Self-expanding valve (n=1,092) | Balloon-expandable valve (n=286) | p-value (self-expanding vs balloon-expandable) |
|---|---|---|---|---|---|---|---|
| Age, years | 82.9±6.2 | 83.0±6.2 | 82.6±6.2 | 0.239 | 83.0±6.2 | 82.5±6.5 | 0.291 |
| Female | 89.5 (1,233) | 89.3 (822) | 89.7 (411) | 0.824 | 89.6 (979) | 88.8 (254) | 0.680 |
| Weight, kg | 64.7±14.7 | 63.5±14.2 | 67.0±15.5 | <0.001 | 63.9±14.2 | 67.5±16.4 | <0.001 |
| Height, cm | 157.7±7.7 | 157.3±7.7 | 158.5±7.7 | 0.006 | 157.4±7.4 | 159.1±8.5 | 0.001 |
| Body surface area, m² | 1.65±0.19 | 1.63±0.19 | 1.68±0.19 | <0.001 | 1.64±0.18 | 1.69±0.21 | <0.001 |
| Body mass index, kg/m² | 25.9±5.4 | 25.6±5.3 | 26.6±5.6 | <0.001 | 25.7±5.3 | 26.6±5.8 | 0.018 |
| Hypertension | 85.5 (1,177) | 84.1 (773) | 88.2 (404) | 0.042 | 84.5 (922) | 89.2 (255) | 0.047 |
| Diabetes mellitus | 26.4 (364) | 25.4 (234) | 28.4 (130) | 0.242 | 26.3 (287) | 26.9 (77) | 0.827 |
| Dyslipidaemia | 51.8 (712) | 53.2 (488) | 49.1 (224) | 0.159 | 52.7 (574) | 48.4 (138) | 0.197 |
| COPD | 11.5 (158) | 11.0 (101) | 12.5 (57) | 0.417 | 10.3 (112) | 16.1 (46) | 0.006 |
| Peripheral artery disease or previous PTA | 11.7 (156) | 12.6 (113) | 9.7 (43) | 0.114 | 12.2 (130) | 9.5 (26) | 0.214 |
| Cerebrovascular disease | 10.4 (143) | 8.7 (80) | 13.8 (63) | 0.004 | 9.3 (101) | 14.7 (42) | 0.007 |
| Previous PCI | 21.9 (301) | 20.3 (186) | 25.3 (115) | 0.035 | 21.4 (233) | 23.9 (68) | 0.355 |
| Previous CABG | 6.0 (82) | 5.6 (51) | 6.8 (31) | 0.365 | 5.6 (61) | 7.3 (21) | 0.268 |
| Previous MI | 9.5 (128) | 9.1 (81) | 10.3 (47) | 0.464 | 9.3 (99) | 10.2 (29) | 0.656 |
| Coronary artery disease | 38.2 (525) | 35.9 (329) | 42.9 (196) | 0.012 | 36.0 (391) | 46.8 (134) | 0.001 |
| PM or ICD | 11.4 (157) | 10.4 (96) | 13.3 (61) | 0.112 | 10.6 (116) | 14.3 (41) | 0.079 |
| Atrial fibrillation | 29.4 (269) | 31.3 (182) | 26.2 (87) | 0.106 | 31.6 (225) | 21.9 (44) | 0.008 |
| Angina | 20.2 (230) | 19.2 (165) | 23.4 (65) | 0.134 | 19.0 (185) | 27.8 (45) | 0.010 |
| NYHA Class III or IV | 67.4 (929) | 65.6 (604) | 71.0 (325) | 0.048 | 66.5 (726) | 71.0 (203) | 0.149 |
| STS-PROM, % | 5.7±4.0 | 5.9±4.3 | 5.5±3.3 | 0.097 | 5.7±4.1 | 5.7±3.6 | 0.951 |
| Values are mean±standard deviation or % (n). The values in bold represent differences between groups with p<0.100. CABG: coronary artery bypass graft; COPD: chronic obstructive pulmonary disease; ICD: implantable cardioverter-defibrillator; MI: myocardial infarction; NYHA: New York Heart Association; PTA: percutaneous transluminal angioplasty; PCI: percutaneous coronary intervention; PM: pacemaker; STS-PROM: Society of Thoracic Surgeons Predicted Risk of Mortality | |||||||