|
Mean AV gradient, mmHg
|
47.7±16.0
|
49.0±16.1
|
45.3±15.5
|
<0.001
|
48.6±16.1
|
44.3±15.3
|
<0.001
|
|
Maximum AV gradient, mmHg
|
77.6±24.8
|
80.0±24.7
|
72.9±24.2
|
<0.001
|
79.0±24.7
|
72.3±24.4
|
<0.001
|
|
EOA, cm2
|
0.64±0.21
|
0.63±0.18
|
0.66±0.25
|
0.023
|
0.64±0.19
|
0.67±0.27
|
0.034
|
|
sPAP, mmHg
|
40.3±13.7
|
39.6±13.0
|
41.9±15.1
|
0.012
|
40.1±13.3
|
41.5±15.2
|
0.189
|
|
TAPSE, mm
|
20.9±3.6
|
21.0±3.7
|
20.3±2.9
|
0.076
|
21.0±3.6
|
20.0±2.9
|
0.059
|
|
Bicuspid AV
|
4.3 (49)
|
3.4 (24)
|
5.8 (25)
|
0.053
|
3.5 (30)
|
7.3 (19)
|
0.007
|
|
Moderate or greater AR
|
6.7 (83)
|
8.3 (67)
|
3.8 (16)
|
0.003
|
7.6 (74)
|
3.4 (9)
|
0.017
|
|
Moderate or greater MR
|
8.8 (112)
|
10.4 (88)
|
5.6 (24)
|
0.004
|
10.4 (105)
|
2.6 (7)
|
<0.001
|
|
Moderate or greater TR
|
6.9 (74)
|
8.1 (54)
|
5.0 (20)
|
0.056
|
7.8 (65)
|
3.8 (9)
|
0.033
|
|
Ejection fraction, %
|
59.2±10.7
|
58.1±10.9
|
61.4±9.9
|
<0.001
|
58.4±10.6
|
62.2±10.2
|
<0.001
|
|
LVEF <40%
|
5.1 (71)
|
6.1 (56)
|
3.3 (15)
|
0.026
|
5.7 (62)
|
3.1 (9)
|
0.085
|
|
CT data
|
|
Mean annular diameter, mm
|
21.2±1.3
|
21.2±1.4
|
21.3±1.1
|
0.084
|
21.2±1.3
|
21.4±1.0
|
0.005
|
|
Maximum diameter, mm
|
23.7±1.8
|
23.6±1.9
|
23.9±1.6
|
<0.001
|
23.6±1.9
|
24.0±1.4
|
0.005
|
|
Minimum diameter, mm
|
18.8±1.8
|
18.8±1.9
|
18.7±1.6
|
0.457
|
18.7±1.9
|
18.9±1.5
|
0.212
|
|
Annular eccentricity
|
1.27±0.17
|
1.27±0.17
|
1.29±0.17
|
0.029
|
1.27±0.17
|
1.28±0.18
|
0.553
|
|
Mean aortic annular perimeter, mm
|
66.9±4.3
|
67.3±3.6
|
66.0±5.3
|
<0.001
|
67.4±3.6
|
65.0±5.9
|
<0.001
|
|
Mean aortic annular area, mm2
|
350.1±34.4
|
347.1±35.5
|
355.5±31.6
|
<0.001
|
346.5±35.1
|
362.3±28.7
|
<0.001
|
|
Area-derived diameter, mm
|
21.1±1.1
|
21.0±1.1
|
21.3±1.0
|
<0.001
|
21.0±1.1
|
21.5±0.9
|
<0.001
|
|
Perimeter-derived diameter, mm
|
21.3±1.5
|
21.4±1.2
|
21.0±1.7
|
<0.001
|
21.5±1.1
|
20.7±1.9
|
<0.001
|
|
Severe leaflet calcification
|
19.3 (185)
|
18.5 (107)
|
20.6 (78)
|
0.421
|
17.1 (115)
|
24.5 (70)
|
0.008
|
|
Severe annular calcification
|
4.4 (38)
|
6.2 (29)
|
2.2 (9)
|
0.005
|
5.6 (34)
|
1.5 (4)
|
0.008
|
|
Severe LVOT calcification
|
4.1 (40)
|
5.7 (34)
|
1.6 (6)
|
0.001
|
5.2 (36)
|
1.4 (4)
|
0.006
|
|
LMCA diameter, mm
|
12.5±2.6
|
12.4±2.5
|
12.6±2.7
|
0.184
|
12.3±2.5
|
12.8±2.6
|
0.003
|
|
RCA diameter, mm
|
14.4±2.8
|
14.2±3.0
|
14.6±2.5
|
0.034
|
14.3±2.9
|
14.7±2.5
|
0.042
|
|
Sinotubular junction diameter, mm
|
25.9±2.7
|
25.8±2.8
|
26.0±2.5
|
0.144
|
25.9±2.8
|
25.9±2.4
|
0.927
|
|
Sinus of Valsalva diameter, mm
|
28.7±2.5
|
28.8±2.5
|
28.6±2.5
|
0.180
|
28.9±2.5
|
28.4±2.5
|
0.013
|
|
Ascending aorta diameter, mm
|
31.9±3.9
|
31.6±3.9
|
32.3±3.9
|
0.016
|
31.9±4.0
|
32.0±3.8
|
0.657
|
|
Porcelain aorta
|
5.1 (61)
|
2.7 (21)
|
9.4 (40)
|
<0.001
|
3.2 (30)
|
11.9 (31)
|
<0.001
|
|
Values are mean±standard deviation or % (n). The values in bold represent differences between groups with p<0.100. AR: aortic regurgitation; AV: aortic valve; CT: computed tomography; EOA: effective orifice area; LMCA: left main coronary artery; LVEF: left ventricular ejection fraction; LVOT: left ventricular outflow tract; MR: mitral regurgitation; RCA: right coronary artery; RV: right ventricular; sPAP: systolic pulmonary artery pressure; TAPSE: tricuspid annular plane systolic excursion; TR: tricuspid regurgitation
|
