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In vivo pig-to-baboon lung xenotransplantation. (A) There was a nonsignificant trend toward improved survival of baboon recipients of pig lungs with h*pvWF (GTKO.hCD46.h*pvWF, red), compared to lungs with pvWF (GTKO.hCD46, blue; GTKO.hCD46 with additional genetics, green); as well as (B) improvement in platelet sequestration in the first 48 h after transplantation (p < .01). Error bars represent standard error of the mean. *p < .05 versus genetic reference
