Figure 5.
Replication kinetics of SARS-CoV-2, IAV, and RSV in air-liquid interface cultures of human bronchial cells coinfected simultaneously with SARS-CoV-2 and IAV or SARS-COV-2 and RSV in the presence (purple bars) or absence of BX795 (grey bars). A, SARS-CoV-2 titers in coinfections with IAV. B, SARS-CoV-2 titers in coinfections with RSV. C, IAV titers in coinfections with SARS-CoV-2. D, RSV titers in coinfections with SARS-CoV-2. SARS-CoV-2 titers are shown in black, IAV in red, and RSV in cyan. Individual titers are shown as circles. Bars represent the mean of 9 values. Error bars represent the standard deviation. Data are combined titers from 3 independent experiments. Statistical significance was tested using Mann-Whitney U tests and separate tests were carried out for individual time points. * P <.05, ** P <.01, *** P <.001. Abbreviations: FFU, focus forming units; IAV, influenza A virus; PFU: plaque forming units; RSV, respiratory syncytial virus; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.
