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. 2023 Mar 17;42(7):1917–1929. doi: 10.1007/s10067-023-06570-3

Table 2.

Laboratory findings and PFT results between the PPF-ASS and non-PPF-ASS groups

Total (n = 72) PPF-ASS (n = 18) Non-PPF-ASS (n = 54) χ2/t p
NLR 4.5 ± 3.5 6.8 ± 5.1 3.8 ± 2.4 N/A 0.001*
LMR 3.1 ± 1.8 3.1 ± 2.1 3.1 ± 1.7 N/A 0.594
PaO2/FiO2 ratio 310.5 ± 84.5 275.4 ± 83.6 322.2 ± 82.2 0.104 0.041*
LDH, U/L 597.2 ± 501.8 886.3 ± 736.8 500.8 ± 354.1 N/A 0.020*
CRP, mg/L 19.9 ± 41.8 39.6 ± 65.7 13.8 ± 28.0 N/A 0.059
ESR, mm/h 21.8 ± 23.7 29.2 ± 33.3 19.3 ± 19.3 N/A 0.298
ALT, U/L 39.8 ± 34.3 50.5 ± 36.5 36.2 ± 33.2 N/A 0.057
AST, U/L 31.3 ± 23.7 37.9 ± 24.7 29.1 ± 23.3 N/A 0.170
Creatine kinase, UI/L 414.9 ± 890.6 805.8 ± 1530.6 284.6 ± 491.8 N/A 0.224
PFT results at diagnosis, % predicted
  FVC 69.1 ± 12.8 65.2 ± 11.1 70.4 ± 13.2  − 1.498 0.139
  DLCO 60.0 ± 14.7 53.8 ± 15.9 62.1 ± 13.8  − 2.126 0.037*

Data are presented as the mean ± standard deviation or n (%)

ASS anti-synthetase syndrome, ALT alanine aminotransferase, AST aspartate aminotransferase, CRP C-reactive protein, DLCO diffusing capacity for carbon monoxide, FVC forced vital capacity, ESR erythrocyte sedimentation rate, LDH lactate dehydrogenase, LMR lymphocyte-to-monocyte ratio, N/A not applicable, NLR neutrophil-to-lymphocyte ratio, PFT pulmonary function test, PPF progressive pulmonary fibrosis

*p < 0.05