Table 1.
Demographic and clinical characteristics of the patients with mpox in this case series.
| PATIENT 1 | PATIENT 2 | PATIENT 3 | PATIENT 4 | PATIENT 5 | PATIENT 6 | PATIENT 7 | PATIENT 8 | PATIENT 9 | PATIENT 10 | PATIENT 11 | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SEX | Male | Male | Male | Male | Male | Male | Male | Transgender female | Male | Male | Male |
| AGE (Years) | 24 | 32 | 30 | 43 | 42 | 30 | 57 | 31 | 33 | 28 | 35 |
| Sexual behavior | MSM | MSM | MSM | MSM | MSM | MSM | MSM | MSM | MSM | MSW | MSM |
| PREVIOUS STis | Syphilis | Syphilis | Neurosyphilis | Syphilis | Syphilis | Not reported | Not reported | Syphilis | Syphilis | Not reported | Syphilis |
| Hepatitis B | Hepatitis B | GC urethritis | |||||||||
| Hepatitis A | CT proctitis | ||||||||||
| CT urethritis | HPV condyloma | ||||||||||
| ASCUS HPV | |||||||||||
| HIV status | Positive on ART | Positive on ART | Positive on ART | Positive on ART | Positive on ART | Positive on ART | Positive on ART | Positive on ART | Positive on ART | Negative | Positive on ART |
| Recent sexual exposure | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes |
| Recent trips abroad | No | No | No | No | No | No | No | No | No | No | No |
| Systemic symptoms | Fever | No | Fever | Fever | Fever | Fever | Myalgia | Fever | Myalgia | Fever | Odynophagia |
| Myalgia | Myalgia | Myalgia | Myalgia | Odynophagia | Myalgia | Odynophagia | |||||
| Asthenia | Asthenia | Asthenia | Asthenia | Asthenia | |||||||
| Anal pain | Odynophagia | ||||||||||
| Headache | |||||||||||
| Lymphadenopathies | Painful inguinal nodes | Painful inguinal nodes | No | No | Painful inguinal nodes | Painful cervical nodes | Painful cervical nodes | Painful cervical nodes | Painful cervical and inguinal nodes | No | No |
| Location of skin lesions | Genital area | Genital area | Genital area | Genital area | Face | Genital area | Oral mucosa | Legs | Genital area | Genital area | Genital area |
| Face | Face | Face | Back | Face | Arms | Arms | Pubic area | Pubic area | Oral mucosa | ||
| Oral mucosa | Back | Legs | Legs | Legs | Thorax | Arms | Face | ||||
| Thorax | Legs | Arms | Arms | Palm of hand | Abdomen | Legs | Neck | ||||
| Back | Arms | Thorax | Pubic area | Face | |||||||
| Legs | Dorsum of hands | Anal area | Oral mucosa | Back | |||||||
| Arms | Abdomen | Oral mucosa (tonsillar hypertrophy) | |||||||||
| Anal area | Sole of foot | ||||||||||
| Hospital admission | Yes (4 days) | No | No | No | No | No | No | No | No | No | No |
| Treatment | Topical antibiotic (fusidic acid) | Topical antibiotic (fusidic acid) | Topical antibiotic (fusidic acid) | Topical antibiotic (fusidic acid) | Topical antibiotic (fusidic acid) | Topical antibiotic (fusidic acid) | Topical antibiotic (fusidic acid) | Topical antibiotic (fusidic acid) | Topical antibiotic (fusidic acid) | Topical antibiotic (fusidic acid) | Topical antibiotic (fusidic acid) |
| Zinc dressing | Zinc dressing | Zinc dressing | Zinc dressing | Zinc dressing | Sodium borate dressing | ||||||
| Topical corticosteroid (betamethasone) | Topical corticosteroid (methylprednisolone) | Topical corticosteroid (betamethasone) | Topical corticosteroid (betamethasone) | Topical corticosteroid (betamethasone) | Topical corticosteroid (betamethasone) | Topical corticosteroid (betamethasone) | |||||
| Topical corticosteroid (triamcinolone acetonide 0.1% in orabase) | Topical corticosteroid (triamcinolone acetonide 0.1% in orabase) | ||||||||||
| Oral analgesic (paracetamol, ibuprofen) | Oral analgesic (paracetamol, ibuprofen) | Oral analgesic (paracetamol, ibuprofen) | Oral analgesic (paracetamol, ibuprofen) | Oral analgesic (paracetamol, ibuprofen) | Oral analgesic (Paracetamol, Ibuprofen) | Oral analgesic (paracetamol, ibuprofen) | Oral analgesic (paracetamol, ibuprofen) | Oral analgesic (paracetamol, ibuprofen) | Oral analgesic (paracetamol, ibuprofen) | Oral analgesic (paracetamol, ibuprofen) | |
| Oral antibiotic (ceftriaxone, azithromycin) | Oral antibiotic (ceftriaxone, azithromycin, penicillin) | Oral antibiotic (ceftriaxone, azithromycin, penicillin) | Oral antibiotic (amoxicillin-clavulanic acid 875/125 mg) | Oral antibiotic (amoxicillin-clavulanic acid 875/125 mg) | Oral antibiotic (amoxicillin-clavulanic acid 875/125 mg) | Oral antibiotic (amoxicillin-clavulanic acid 875/125 mg) | Oral antibiotic (amoxicillin-clavulanic acid 875/125 mg) | Oral antibiotic (amoxicillin-clavulanic acid 875/125 mg) | |||
| IV antibiotic (amoxicillin-clavulanic acid 875/125 mg) | IV antibiotic (amoxicillin-clavulanic acid 2 g u.d.) | ||||||||||
| Diagnostic test | Orthopoxvirus PCR | Orthopoxvirus PCR | Orthopoxvirus PCR | Orthopoxvirus PCR | Orthopoxvirus PCR | Orthopoxvirus PCR | Orthopoxvirus PCR | Orthopoxvirus PCR | Orthopoxvirus PCR | Orthopoxvirus PCR | Orthopoxvirus PCR |
| Time to hospital care (days) | 2 | 3 | 9 | 4 | 6 | 7 | 5 | 1 | 4 | 2 | 2 |
| Complication | Superinfection | Ulceration | Ulceration | Cellulitis | Cellulitis | Ulceration | Pharyngitis | Tonsillitis | Ulceration | Ulceration | Ulceration |
| Ulceration | Penile edema | Penile edema |
MSM, men who have sex with men; CT, Chlamydia trachomatis; ASCUS, atypical squamous cells of undetermined significance; ART, antiretroviral therapy; GC, gonococcal.