TABLE 4.
Receiver operating characteristics analysis for parameters of bilateral corneal biomechanics and tomography.
| Parameters | AUROC | Sig. | 95% CI | Cut-off | Sensitivity (%) | Specificity (%) |
|---|---|---|---|---|---|---|
| ΔA1V (m/s) | 0.719 | <0.001 | 0.666 to 0.773 | 0.02 | 53.8 | 83.6 |
| ΔA2V (m/s) | 0.747 | <0.001 | 0.695 to 0.798 | 0.03 | 57.2 | 86.8 |
| ΔA1DeflA (mm) | 0.779 | <0.001 | 0.731 to 0.827 | 0.01 | 62.4 | 81.5 |
| ΔA2DeflA (mm) | 0.710 | <0.001 | 0.656 to 0.765 | 0.02 | 49.7 | 87.3 |
| ΔDeflA Max (mm) | 0.770 | <0.001 | 0.721 to 0.819 | 0.09 | 53.2 | 91.0 |
| ΔMax ICR (mm−1) | 0.805 | <0.001 | 0.758 to 0.853 | 0.02 | 61.5 | 89.8 |
| ΔDAR2 | 0.889 | <0.001 | 0.854 to 0.924 | 0.41 | 76.9 | 91.5 |
| ΔDAR1 | 0.795 | <0.001 | 0.747 to 0.843 | 0.05 | 59.1 | 90.5 |
| ΔARTh | 0.780 | <0.001 | 0.732 to 0.829 | 100.47 | 57.8 | 88.9 |
| ΔIR (mm-1) | 0.884 | <0.001 | 0.845 to 0.922 | 0.93 | 80.3 | 91.5 |
| ΔSP-A1 (mmHg/mm) | 0.826 | <0.001 | 0.783 to 0.869 | 12.90 | 68.2 | 82.5 |
| ΔCBI | 0.531 | 0.138 | 0.468 to 0.595 | 0.50 | 30.6 | 95.8 |
| ΔTBI | 0.750 | <0.001 | 0.688 to 0.812 | 0.01 a | 71.7 | 94.2 |
| ΔSSI | 0.767 | <0.001 | 0.717 to 0.816 | 0.11 | 61.8 | 83.1 |
| ΔBAD-D | 0.958 | <0.001 | 0.934 to 0.982 | 2.12 | 89.6 | 97.4 |
| LRM-1 | 0.922 | <0.001 | 0.893 to 0.952 | 0.54 | 78.6 | 95.8 |
| LRM-2 | 0.998 | <0.001 | 0.996 to 1.000 | 0.37 | 98.8 | 97.9 |
Notes: AUROC, area under the curves of receiver operating characteristic; Sig, significance; 95% CI, 95% confidence interval for AUROC; Cut-off, the threshold values; ΔA1V, asymmetry of velocity at the first applanation; ΔA2V, asymmetry of velocity at the second applanation; ΔA1DeflA, asymmetry of the deflection amplitude at the first applanation; ΔA2DeflA, asymmetry of the deflection amplitude at the second applanation; ΔDeflA Max, asymmetry of the maximum deflection amplitude; ΔMax ICR, asymmetry of the maximum inverse concave radius; ΔDAR2, asymmetry of the deformation amplitude ratio at 2 mm; ΔDAR1, asymmetry of the deformation amplitude ratio at 1 mm; ΔARTh, asymmetry of the Ambrosio Relational Thickness horizontal; ΔIR, asymmetry of the integrated radius; ΔSP-A1, asymmetry of the stiffness parameter at the first applanation; ΔCBI, asymmetry of the Corvis Biomechanical Index; ΔTBI, asymmetry of the Tomographic and Biomechanical Index; ΔSSI, asymmetry of the stress-strain index; ΔBAD-D, asymmetry of the Belin/Ambrosio Enhanced Ectasia Deviation value; mmHg/mm, millimeter of mercury per millimeter; mm, millimeter; ms, millisecond; m/s, meter per second; LRM-1, Logistic regression model-1, and LRM-2, Logistic regression model-2.
A smaller value indicates a more positive test.