TABLE 3.
Correct versus incorrect answers of the studied pharmacists toward the 28 drug-drug interaction pair (DDI).
| Drug–drug interaction pair | Incorrect n (%) | Correct n (%) | p-value | ||
|---|---|---|---|---|---|
| 1 | Digoxin/Erythromycin | 124 (84.4%) | 23 (15.6%) | <0.001 a | |
| 2 | Clarithromycin/Simvastatin | 77 (52.4%) | 70 (47.6%) | 0.564 | |
| 3 | Phenytoin/Cimetidine | 116 (78.9%) | 31 (21.1%) | <0.001 a | |
| 4 | Itraconazole/Quinidine | 68 (46.3%) | 79 (53.7%) | 0.364 | |
| 5 | Theophylline/Omeprazole | 131 (89.1%) | 16 (10.9%) | <0.001 a | |
| 6 | Sildenafil/Isosorbide mononitrate | 27 (18.4%) | 120 (81.6%) | <0.001 a | |
| 7 | Ibuprofen/Furosemide | 81 (55.1%) | 66 (44.9%) | 0.216 | |
| 8 | Amoxicillin/Acetaminophen | 34 (23.1%) | 113 (76.9%) | <0.001 a | |
| 9 | Pimozide/Ketoconazole | 94 (63.9%) | 53 (36.1%) | 0.001 a | |
| 10 | Fluconazole/Phenytoin | 108 (73.5%) | 39 (26.5%) | <0.001 a | |
| 11 | Digoxin/Sildenafil | 106 (72.1%) | 41 (27.9%) | <0.001 a | |
| 12 | Alprazolam/Itraconazole | 86 (58.5%) | 61 (41.5%) | 0.039 a | |
| 13 | Fexofenadine HCL/Metoprolol | 73 (49.7%) | 74 (50.3%) | 0.934 | |
| 14 | Amiodarone/Warfarin | 93 (63.3%) | 54 (36.7%) | 0.001 a | |
| 15 | Cyclosporine/Rifampicin | 110 (74.8%) | 37 (25.2%) | <0.001 a | |
| 16 | Raloxifene/Alendronate | 108 (73.5%) | 39 (26.5%) | <0.001 a | |
| 17 | Warfarin and sulfamethoxazole/Trimethoprim | 111 (75.5%) | 36 (24.5%) | <0.001 a | |
| 18 | Meloxicam/Gabapentin | 70 (47.6%) | 77 (52.4%) | 0.564 | |
| 19 | Methotrexate/Probenecid | 96 (65.3%) | 51 (34.7%) | <0.001 a | |
| 20 | Phenytoin/Warfarin | 110 (74.8%) | 37 (25.2%) | <0.001 a | |
| 21 | Meperidine/Phenelzine | 96 (65.3%) | 51 (34.7%) | <0.001 a | |
| 22 | Rosuvastatin/Propranolol | 80 (54.4%) | 67 (45.6%) | 0.284 | |
| 23 | Omeprazole/Clopidogrel | 73 (49.7%) | 74 (50.3%) | 0.934 | |
| 24 | Amiodarone/Simvastatin | 111 (75.5%) | 36 (24.5%) | <0.001 a | |
| 25 | Diphenhydramine/Warfarin | 93 (63.3%) | 54 (36.7%) | 0.001 a | |
| 26 | Simvastatin/Itraconazole | 92 (62.6%) | 55 (37.4%) | 0.002 a | |
| 27 | Dopamine/Phenytoin | 112 (76.2%) | 35 (23.8%) | <0.001 a | |
| 28 | Acetaminophen/Celecoxib | 63 (42.9%) | 84 (57.1%) | 0.083 | |
| N | Min-Max | Mean ± SD | Median | ||
| Knowledge on drug-drug interactions | 147 | 0.00–89.29 | 38.22 ± 22.0 | 35.71 | |
a
Significant using Chi-Square Test at 0.05 level.