Table 2.

Prevalence of dispensed benzodiazepine and opioid prescriptions among people with healthcare encounters for benzodiazepine-related toxicity, 2013 to 2020

Measure	2013	2014	2015	2016	2017	2018	2019	2020	p-value
Number of benzodiazepine-related toxicity encounters	3820	3856	3967	4149	4693	4487	3874	3828
Benzodiazepine prescribing history
Active prescription	2332 (61.1%)	2419 (62.7%)	2384 (60.1%)	2400 (57.9%)	2445 (52.1%)	2434 (54.3%)	2086 (53.9%)	1872 (48.9%)	< 0.0001
Prescription in the previous 30 days	2417 (63.3%)	2475 (64.2%)	2492 (62.8%)	2525 (60.9%)	2621 (55.9%)	2566 (57.2%)	2259 (58.3%)	2045 (53.4%)	< 0.0001
Prescription in the previous 180 days	2945 (77.1%)	3033 (78.7%)	3085 (77.8%)	3123 (75.3%)	3302 (70.4%)	3241 (72.2%)	2843 (73.4%)	2571 (67.2%)	< 0.0001
Active opioid prescription	738 (19.3%)	714 (18.5%)	741 (18.7%)	662 (16.0%)	716 (15.3%)	671 (15.0%)	580 (15.0%)	539 (14.1%)	< 0.0001
Active opioid and benzodiazepine prescriptions	600 (15.7%)	569 (14.8%)	577 (14.5%)	500 (12.1%)	532 (11.3%)	507 (11.3%)	435 (11.2%)	391 (10.2%)	< 0.0001