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. Author manuscript; available in PMC: 2023 Jun 14.
Published in final edited form as: Value Health. 2020 Jul 18;23(7):851–861. doi: 10.1016/j.jval.2020.03.007

Table 4.

Preferences for characteristics of HIV antiretroviral therapy: Results from a scale-adjusted latent class model (N=403)

Preference classes
Class 1 Class 2 Class 3 Class 4 Class 5
Class size 40.2% 24.3% 20.9% 10.2% 4.5%
Coefficient estimates
Dosing 1 pill once daily 1.391 1.094 1.343 3.784 −0.190
2 pills once daily −0.058 0.882 −0.390 −0.544 −0.050
3 pills once daily −0.862 −0.387 −1.549 −3.210 −0.258
1 pill twice daily −0.472 −1.590 0.595 −0.030 0.498
Administration Meal requirement −0.527 −2.631 1.047 0.490 −0.267
Large pill 0.074 1.203 −1.905 0.007 −0.017
Neither 0.453 1.428 0.858 −0.497 0.284
Side effect None 3.046 4.655 3.191 2.909 0.091
Moderate −3.046 −4.655 −3.191 −2.909 −0.091
Long-term risk Low 2.663 3.465 2.244 1.744 0.593
High −2.663 −3.465 −2.244 −1.744 −0.593
Intercept 1.057 0.559 0.317 −0.304 −1.630
Study cohort Duke −0.012 −0.203 0.341 0.208 −0.334
South Carolina −0.110 0.482 0.576 −0.079 −0.870
Online panel 0.122 −0.280 −0.917 −0.129 1.203
Coefficient ranges
Dosing 2.25 2.68 2.89 6.99 0.76
Administration 0.98 4.06 2.95 0.99 0.55
Side effect 6.09 9.31 6.38 5.82 0.18
Long-term risk 5.33 6.93 4.49 3.49 1.19
Importance of attributes
Dosing 15% 12% 17% 40% 28%
Administration 7% 18% 18% 6% 21%
Side effect 42% 41% 38% 34% 7%
Long-term risk 36% 30% 27% 20% 44%

Notes to Table 4.

Respondents were asked to complete 16 choice tasks; each choice task was comprised of 3 treatment options. A total of 16 questions were skipped across the three cohorts.

The relative importance of attribute levels is described by coefficient estimates from a scale-adjusted latent class model with 5 preference classes and 3 continuous normally distributed scale factors.

The relative importance of attributes is described by the range of each attribute’s coefficient estimates as a share of the total range across attributes.