Table 4.
Preferences for characteristics of HIV antiretroviral therapy: Results from a scale-adjusted latent class model (N=403)
| Preference classes | ||||||
|---|---|---|---|---|---|---|
| Class 1 | Class 2 | Class 3 | Class 4 | Class 5 | ||
| Class size | 40.2% | 24.3% | 20.9% | 10.2% | 4.5% | |
| Coefficient estimates | ||||||
| Dosing | 1 pill once daily | 1.391 | 1.094 | 1.343 | 3.784 | −0.190 |
| 2 pills once daily | −0.058 | 0.882 | −0.390 | −0.544 | −0.050 | |
| 3 pills once daily | −0.862 | −0.387 | −1.549 | −3.210 | −0.258 | |
| 1 pill twice daily | −0.472 | −1.590 | 0.595 | −0.030 | 0.498 | |
| Administration | Meal requirement | −0.527 | −2.631 | 1.047 | 0.490 | −0.267 |
| Large pill | 0.074 | 1.203 | −1.905 | 0.007 | −0.017 | |
| Neither | 0.453 | 1.428 | 0.858 | −0.497 | 0.284 | |
| Side effect | None | 3.046 | 4.655 | 3.191 | 2.909 | 0.091 |
| Moderate | −3.046 | −4.655 | −3.191 | −2.909 | −0.091 | |
| Long-term risk | Low | 2.663 | 3.465 | 2.244 | 1.744 | 0.593 |
| High | −2.663 | −3.465 | −2.244 | −1.744 | −0.593 | |
| Intercept | 1.057 | 0.559 | 0.317 | −0.304 | −1.630 | |
| Study cohort | Duke | −0.012 | −0.203 | 0.341 | 0.208 | −0.334 |
| South Carolina | −0.110 | 0.482 | 0.576 | −0.079 | −0.870 | |
| Online panel | 0.122 | −0.280 | −0.917 | −0.129 | 1.203 | |
| Coefficient ranges | ||||||
| Dosing | 2.25 | 2.68 | 2.89 | 6.99 | 0.76 | |
| Administration | 0.98 | 4.06 | 2.95 | 0.99 | 0.55 | |
| Side effect | 6.09 | 9.31 | 6.38 | 5.82 | 0.18 | |
| Long-term risk | 5.33 | 6.93 | 4.49 | 3.49 | 1.19 | |
| Importance of attributes | ||||||
| Dosing | 15% | 12% | 17% | 40% | 28% | |
| Administration | 7% | 18% | 18% | 6% | 21% | |
| Side effect | 42% | 41% | 38% | 34% | 7% | |
| Long-term risk | 36% | 30% | 27% | 20% | 44% | |
Notes to Table 4.
Respondents were asked to complete 16 choice tasks; each choice task was comprised of 3 treatment options. A total of 16 questions were skipped across the three cohorts.
The relative importance of attribute levels is described by coefficient estimates from a scale-adjusted latent class model with 5 preference classes and 3 continuous normally distributed scale factors.
The relative importance of attributes is described by the range of each attribute’s coefficient estimates as a share of the total range across attributes.