Table 2.
Sensitivity, Specificity, Positive Predictive Value (PPV), Negative Predictive Value (NPV), and Accuracy for the Motor tic, Obsession and compulsion, and Vocal tic Evaluation Survey (MOVES) compared with expert clinical assessment by cutoffs
| Cutoff | Sensitivity | Specificity | Youden Index | TP | FP | FN | TN | Accuracy |
|---|---|---|---|---|---|---|---|---|
| 0 | 100% | 0% | 0.00 | 144 | 73 | 0 | 0 | 66% |
| 1 | 100% | 33% | 0.33 | 144 | 49 | 24 | 0 | 77% |
| 2 | 99% | 44% | 0.42 | 142 | 41 | 32 | 2 | 80% |
| 3 | 97% | 63% | 0.60 | 139 | 27 | 46 | 5 | 85% |
| 4 | 93% | 70% | 0.63 | 134 | 22 | 51 | 10 | 85% |
| 5* | 90% | 77% | 0.66 | 129 | 17 | 56 | 15 | 85% |
| 6 | 86% | 79% | 0.66 | 124 | 15 | 58 | 20 | 84% |
| 7 | 82% | 84% | 0.66 | 118 | 12 | 61 | 26 | 82% |
| 8 | 78% | 84% | 0.62 | 113 | 12 | 61 | 31 | 80% |
| 9 | 76% | 86% | 0.62 | 109 | 10 | 63 | 35 | 79% |
| 10 | 74% | 90% | 0.64 | 106 | 7 | 66 | 38 | 79% |
| 11 | 69% | 90% | 0.60 | 100 | 7 | 66 | 44 | 76% |
| 12 | 67% | 93% | 0.60 | 96 | 5 | 68 | 48 | 76% |
| 13 | 59% | 96% | 0.55 | 85 | 3 | 70 | 59 | 71% |
| 14 | 52% | 97% | 0.49 | 75 | 2 | 71 | 69 | 67% |
| 15 | 47% | 99% | 0.45 | 67 | 1 | 72 | 77 | 64% |
| 20 | 28% | 100% | 0.28 | 41 | 0 | 73 | 103 | 53% |
| 25 | 18% | 100% | 0.18 | 26 | 0 | 73 | 118 | 46% |
| 35 | 9% | 100% | 0.09 | 13 | 0 | 73 | 131 | 40% |
| 45 | 1% | 100% | 0.01 | 1 | 0 | 73 | 143 | 34% |
TP=true positives; FP=false positives; FN=false negatives; TN=true negative;
We identified a cut-off of 5 as optimal for balancing sensitivity and specificity; Other cutoffs may be chosen based on the intended use of the screener.