Table 3.
Sensitivity, Specificity, Positive Predictive Value (PPV), Negative Predictive Value (NPV), and Accuracy for the 6-item Motor tic, Obsession and compulsion, and Vocal tic Evaluation Survey (MOVES-6) compared with expert clinical assessment by cutoffs
| Cutoff | Sensitivity | Specificity | Youden Index | TP | FP | FN | TN | Accuracy |
|---|---|---|---|---|---|---|---|---|
| 0 | 100% | 0% | 0.00 | 144 | 73 | 0 | 0 | 66% |
| 1 | 98% | 52% | 0.50 | 141 | 35 | 38 | 3 | 82% |
| 2 | 94% | 77% | 0.71 | 136 | 17 | 56 | 8 | 88% |
| 3* | 88% | 86% | 0.74 | 127 | 10 | 63 | 17 | 88% |
| 4 | 79% | 95% | 0.74 | 114 | 4 | 69 | 30 | 84% |
| 5 | 71% | 96% | 0.67 | 102 | 3 | 70 | 42 | 79% |
| 6 | 61% | 100% | 0.61 | 88 | 0 | 73 | 56 | 74% |
| 7 | 51% | 100% | 0.51 | 74 | 0 | 73 | 70 | 68% |
| 8 | 43% | 100% | 0.43 | 62 | 0 | 73 | 82 | 62% |
| 9 | 39% | 100% | 0.39 | 56 | 0 | 73 | 88 | 59% |
| 10 | 28% | 100% | 0.28 | 41 | 0 | 73 | 103 | 53% |
| 15 | 3% | 100% | 0.03 | 4 | 0 | 73 | 140 | 35% |
| 18 | 1% | 100% | 0.01 | 1 | 0 | 73 | 143 | 34% |
TP=true positives; FP=false positives; FN=false negatives; TN=true negatives
*
We identified a cutoff as 3 as optimal for balancing sensitivity and specificity; Other cutoffs may be chosen based on the intended use of the screener.