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. 2023 Jun 14;8(8):732–741. doi: 10.1001/jamacardio.2023.1505

Figure 1. Predicted Probability of a Composite Cardiovascular (CV) Event at 4 Years by Continuous Urine Albumin to Creatinine Ratio (UACR) and Estimated Glomerular Filtration Rate (eGFR).

Figure 1.

Patients with eGFR less than 60 (A) or greater than or equal to 60 (B). Patients with UACR less than 300 mg/g (C) or greater than or equal to 300 mg/g (D). The Cox proportional hazards model was fitted with the covariates treatment, study, CV disease history, region, sex, and race, and the continuous covariates age, hemoglobin A1c, systolic blood pressure, baseline UACR (log transformed), and eGFR at baseline. Cubic B-splines were used for log-transformed UACR (A and B) and eGFR (C and D). Vertical lines highlight predicted probability of composite CV events at key UACR and eGFR thresholds.