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Induction of CD1 promoter activity by Sp1 was abolished by GKLF but not by truncated GKLF-1580. L293 cells were transfected with pCD1-963 Luc construct and expression plasmids containing GKLF and Sp1 as indicated. Luciferase and β-galactosidase activities were determined 48 h later. Data were expressed as fold increases over control (cells transfected with pCD1-963 Luc only) and presented as means ± S.E. of three separate experiments.
