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. 2023 May 22;15(5):2544–2558. doi: 10.21037/jtd-22-1731

Table 2. Correlation between lung metabolites and lung function parameters in human participants.

Lung function parameters Values Leucine Glutamic acid Linoleylcarnitine Glycine Propionylcarnitine Fumaric acid Malic acid
FVC (%pred) r 0.496* 0.377 0.227 −0.073 −0.283 −0.356 0.005
P 0.026 0.101 0.336 0.758 0.227 0.123 0.985
FEV1 (%pred) r 0.714** 0.650* 0.373 −0.046 −0.445* −0.589** −0.371
P <0.01 0.02 0.105 0.076 0.049 0.006 0.107
FEV1/FVC (%) r 0.501* 0.568** 0.331 −0.453* −0.432 −0.420 −0.477*
P 0.025 0.009 0.154 0.045 0.057 0.066 0.034
TLC (%pred) r −0.619** −0.373 −0.131 0.302 0.358 0.371 0.451*
P 0.004 0.106 0.582 0.196 0.121 0.107 0.046
DLCO (%pred) r 0.648** 0.542* 0.338 −0.438 −0.433 −0.466* −0.528*
P 0.002 0.014 0.145 0.054 0.056 0.038 0.017

*, P<0.05; **, P<0.01. FVC (%pred), forced vital capacity percent predicted; FEV1 (%pred), forced expiratory volume in one second percent predicted; TLC (%pred), total lung capacity percent predicted; DLCO (%pred), diffusing capacity of lung for carbon monoxide percent predicted.