Table 2. Insertion technique and outcome of patients on V-V ECMO, indicated for all indications as well as for subgroups with different indications.
| Variables | All indications (n=221) | ARDS (n=138) | Bridge to lung transplantation (n=17) | Primary graft dysfunction after lung transplantation (n=4) | Other pulmonary disease indications (n=62) |
|---|---|---|---|---|---|
| ECMO, n (%) | |||||
| External insertion† | 54 (24.4) | 43 (31.2) | 0 (0.0) | 0 (0.0) | 11 (17.7) |
| Insertion technique | |||||
| Seldinger peripheral | 218 (98.6) | 138 (100.0) | 15 (88.2) | 3 (75.0) | 62 (100.0) |
| Surgical peripheral | 3 (1.4) | 0 (0.0) | 2 (11.8) | 1 (25.0) | 0 (0.0) |
| Surgical central | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
| Successful weaning | 136 (61.5) | 96 (69.6) | 2 (11.8) | 3 (75.0) | 35 (56.5) |
| Mortality, n (%) | |||||
| In-hospital mortality | 83 (37.6) | 50 (36.2) | 5 (29.4) | 1 (25.0) | 27 (43.5) |
| Death during ECMO therapy | 68 (30.8) | 42 (30.4) | 1 (5.9) | 1 (25.0) | 24 (38.7) |
| In-hospital death after ECMO weaning | 15 (6.8) | 8 (5.8) | 4 (23.5) | 0 (0.0) | 3 (4.8) |
| 30-day mortality (n=210)†† | 66 (31.4) | 45 (29.5) | 4 (23.5) | 1 (25.0) | 27 (38.6) |
| Duration | |||||
| ECMO (days) | 7.0 (3.0 to 15.0) | 7.0 (4.0 to 14.8) | 23.0 (12.0 to 31.0) | 12.5 (11.5 to 13.0) | 5.0 (2.0 to 11.5) |
| Ventilation (days) | 13.0 (6.0 to 28.0) | 14.5 (7.2 to 30.8) | 20.0 (5.0 to 28.0) | 42.0 (24.8 to 54.5) | 9.5 (3.2 to 19.0) |
| ICU (days) | 17.0 (9.0 to 35.0) | 17.0 (10.0 to 33.8) | 32.0 (21.0 to 56.0) | 47.0 (36.0 to 55.0) | 13.0 (7.0 to 30.2) |
| Hospital stay (days) | 26.0 (13.0 to 48.0) | 27.5 (13.0 to 48.0) | 38.8 (32.0 to 73.0) | 62.5 (44.8 to 80.2) | 20.0 (11.0 to 35.0) |
Data presents as median (IQR) or n (%). †, ECMO insertion by University Hospital Zurich outreach team in another hospital before transfer to University Hospital Zurich for definitive care; ††, deviating number of patients (210 instead of the total number of 221) due to loss of follow up on day 30 after ECMO insertion. V-V ECMO, veno-venous extracorporeal membrane oxygenation; ECMO, extracorporeal membrane oxygenation; ARDS, acute respiratory distress syndrome; ICU, intensive care unit; IQR, interquartile range.