Figure 3.

LRP1 KO decreases CXCR4 expression in adult NSCs. Representative images with orthogonal views are shown from SVZs in (A, C) control (Cntrl) and (B, D) LRP1-KO mice 2-weeks after MCAO of (A, B) CXCR4 immunostained cells, (C, D) channels were merged to show tdTomato (red), CXCR4 (green), and nuclear DAPI (blue). (E) Quantification of CXCR4 intensity in tdTomato+ cells (n = 5-6 mice/group). (F) qRT-PCR of CXCR4 was in tdTomato+ sorted cells (n = 4). Results are averages ± SEM, differences were tested using ANOVA followed by Tukey’s HSD.