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. 2023 May 30;15:1134096. doi: 10.3389/fnagi.2023.1134096

Table 2.

A summary of the literature included from the PubMed search in the full text review (n = 25) (Mandal et al., 2015; Zorluoglu et al., 2015; Zylstra et al., 2018; Leorin et al., 2019; Sabbagh et al., 2020; Yousaf et al., 2020; Boyd et al., 2021; Li et al., 2021; Paddick et al., 2021; Hackett et al., 2022).

Type of literature # Apps featured Main themes Date App target audience Summary
Clinical Trial or Single App Design Scheme 11 • AltoidaML
• MyMindCheck
• InspireD
• NPI
• SmartPrompt
• NMI
• Alzheed
• MCS
• Therapy/Treatment (1)
• App Design/Quality (3)
• Monitoring Symptoms (3)
• Screening (4)
• 2022 (2)
• 2021 (5)
• 2020 (1)
• 2019 (2)
• 2015 (1)
• PwD (7)
• Caregivers (4)
• Healthcare professionals (1)
• MCI (3)
• Older adults/controls (6)
Tracking use of apps in PwD; Co-design is important for use/adherence; Potential measurement of longitudinal symptoms; Tracking eye-gaze (2); CV risk factor improvement in individuals at risk; Apps are pragmatic; audio recordings, gait, sit-to-stand tests; monitoring BPSD progression; tapping speeds/gait/voice; Screening apps in rural areas; Reminder apps usability; Machine learning for long-term prediction models of MCI progression; Privacy risks mentioned consistently
Literature Review or Multi-App Analysis 12 • Dementia Talk
• Alzheimer's Manager
• CogSelfTest
• BrainCheck Memory
• BrainTest
• MemTrax
• Minstrong Health
• NeuraMetrix
• Altoida
• DementiaTest
• ConsultGeri
• MCS
• eSLUMS
• Mental Health Test
• iVitality
• Color-Shape Test
• DelApp
• MOBI-COG
• Dementia Screener
• Edinburgh Dementia App
• App Design/Quality (2)
• Screening (4)
• Monitoring Symptoms (5)
• Privacy (2)
• 2022 (2)
• 2021 (1)
• 2020 (2)
• 2019 (2)
• 2018 (2)
• 2017
• 2015
• 2014
• Older Adults (3)
• Caregivers (3)
• PwD (7)
Most cognitive games on commercially available apps are not associated with clinical research; Many apps are available for caregivers but most do not have tracking abilities; Apps designed for PwD are often difficult for users due to cognitive impairments; Privacy and data collection mentioned consistently; Great potential for mHealth but current shortage of apps for PwD; Screening potential for cognitive impairment is great with mobile apps but validation is difficult, technological fluency is a concern; Passive monitoring is a potential screening tool via wearable technologies, speech detection
Article 2 n/a • Monitoring Symptoms (1)
• Potential App Design (1)
• 2020
• 2019
PwD (2) AI shows accuracy in detecting speech changes between AD and control groups; Privacy is a concern; Co-design of apps with users and professionals is important

Search inclusion criteria are listed in Table 1. Some articles had more than one main theme and multiple target audiences. People living with Dementia (PwD). Cardiovascular risk (CV).