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. 2023 Jun 2;8(23):20196–20233. doi: 10.1021/acsomega.3c01558

Figure 7.

Figure 7

Optimization of PD0407824 (41) to enhance selectivity, potency, and solubility (adopted from Palmer et al.;104 Smaill, Baker et al.;105 and Smaill, Lee et al.106).