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. 2023 Jun 2;8(23):20196–20233. doi: 10.1021/acsomega.3c01558

Scheme 19. Synthesis of Pyrimidine-Based Tricyclics (XI).

Scheme 19

From 99 to 113 (adapted from Woods et al.139) and from 20 to 113 (adapted from Tian et al.140).