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. 2023 Jun 2;8(23):20196–20233. doi: 10.1021/acsomega.3c01558

Table 2. Pyrrolocarbazole Analogues (XVII)a.

comp R R1 R2 IC50 (nM)
44 H Ph H 130
45 H 2-Cl Bn H 11
46 H 2,6-diCl Bn H 28
47 H 2-Cl Bn (CH2)3OH 9
48 H 2-Cl Bn (CH2)2CONH2 6
49 (CH2)4NMe2 2-Cl Bn H 49
50 O(CH2)3Nmorph 2-Cl Bn (CH2)2OH 15
a

Bn stands for benzene, Ph for phenyl, and morph for morpholine.