Table 2.
Phase circular correlations
Threshold | Phase circular correlation | ||||||
---|---|---|---|---|---|---|---|
Expression |
Periodicity (human, P. vivax), % |
P. vivax | Wall time | Adjusted by recent sleep | Adjusted by recent wake | Adjusted by usual sleep | Adjusted by usual wake |
10 | (1, 3) | 0.56 (0.048) | 0.45 (0.09) | 0.41 (0.119) | 0.24 (0.249) | 0.27 (0.229) | 0.156 (0.336) |
(3, 3) | 0.70 (0.019) | 0.31 (0.178) | 0.44 (0.102) | 0.16 (0.338) | 0.22 (0.235) | 0.23 (0.298) | |
(5, 5) | 0.66 (0.037) | 0.20 (0.291) | 0.33 (0.160) | 0.06 (0.430) | 0.18 (0.276) | 0.18 (0.362) | |
(10, 5) | 0.71 (0.022) | 0.02 (0.553) | 0.11 (0.337) | −0.11 (0.594) | −0.09 (0.630) | 0.01 (0.608) | |
5 | (3, 3) | 0.59 (0.053) | 0.15 (0.355) | 0.35 (0.148) | 0.04 (0.449) | 0.10 (0.363) | 0.14 (0.407) |
(5, 5) | 0.65 (0.039) | 0.08 (0.450) | 0.21 (0.252) | −0.10 (0.574) | 0.01 (0.471) | 0.03 (0.562) | |
(10, 5) | 0.63 (0.062) | −0.07 (0.648) | 0.05 (0.447) | −0.16 (0.638) | −0.15 (0.738) | −0.10 (0.673) | |
1 | (3, 3) | 0.57 (0.054) | 0.18 (0.322) | 0.33 (0.176) | −0.12 (0.612) | 0.08 (0.416) | −0.01 (0.526) |
(5, 5) | 0.60 (0.048) | −0.02 (0.553) | 0.08 (0.410) | −0.23 (0.718) | −0.12 (0.659) | −0.15 (0.666) | |
(10, 5) | 0.62 (0.043) | 0.01 (0.517) | 0.11 (0.376) | −0.14 (0.621) | −0.06 (0.587) | −0.08 (0.623) |
The circular correlations between human circadian phases and either P. vivax phases, wall times or sleep/wake-adjusted wall times. Empirical P values are given in parentheses. Periodic genes are taken to be those whose maximum expression across the time series is at least the specified expression threshold in QN TPMs and which exhibit at least the same degree of periodicity as the top X% of these genes when ranked by the JTK periodicity scores. Pairs of periodicity thresholds specify those used for humans and P. vivax samples.